Protein Alignment Galphao and GNAT3

DIOPT Version :9

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001095856.1
• Gene: GNAT3 / 346562
• HGNCID: 22800
• Length: 354
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 205/355 - (57%)
• Similarity: 270/355 - (76%)
• Gaps: 2/355 - (0%)

  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65
            ||...|:|.:.:|.||:.:|:.|:||..:.|:.:|||||||||||||||||||||||::|::.::
Human     1 MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNGYSEQE 65

  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKR 130
            ..:::.|:||||:||::||::||.||.|.|.|.....|.:.::.:...:.| ...:.:|...:||
Human    66 CMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLED-GGMTPQLAEVIKR 129

  Fly   131 LWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNL 195
            ||:|.|:|.||.|::||||||||.|:|:||||:.|..|.|.|||:|.:|||||||:|..||||:|
Human   130 LWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRVKTTGIIETQFSFKDL 194

  Fly   196 NFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWF 260
            :|::||||||||||||||||||.||.||||.|:|.||.||.|||..|||.|||.||:||||:|:|
Human   195 HFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEEVNRMHESLHLFNSICNHKYF 259

  Fly   261 TDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYIQAQFEAKN-KSTSKEIYCHMT 324
            :.|||:|||||||:|:||:.|..|:||||||||...:.:|..||:.||...| |...||||.|||
Human   260 STTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDAGNYIKNQFLDLNLKKEDKEIYSHMT 324

  Fly   325 CATDTNNIQFVFDAVTDVIIANNLRGCGLY 354
            |||||.|::||||||||:||..||:.|||:
Human   325 CATDTQNVKFVFDAVTDIIIKENLKDCGLF 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	188/314 (60%)
GNAT3	NP_001095856.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27		10/25 (40%)
		G-alpha	34..348	CDD:206639	188/314 (60%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	173..181		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	196..205		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	265..272		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D406662at33208
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100285
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.730