Protein Alignment Galphao and Gna13

DIOPT Version :10

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001013137.1
• Gene: Gna13 / 303634
• RGDID: 1310221
• Length: 377
• Species: Rattus norvegicus
• Alignment Length: 357
• Identity: 151/357 - (42%)
• Similarity: 217/357 - (60%)
• Gaps: 10/357 - (2%)

  Fly     2 GCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDF 66
            ||..:..|.....:|:.|::.|..:.....:.:|:||||||||||||.:|||:|||...|.....
  Rat    17 GCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAR 81

  Fly    67 KQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERE--SDAKMVFD-----VCQRMHDTEPFSEEL 124
            :::||.:|||.|:.:..::.|...|.|.:.:|:.:  .|..|.||     ..|.|.:|..|. :.
  Rat    82 EEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQVHGDKLMAFDTRAPMAAQGMVETRVFL-QY 145

  Fly   125 LAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVH 189
            |.|::.||.|:|:|..:.|..|:||.:|.|||||:||:||..||.|::||||..|..|.||.|..
  Rat   146 LPAIRALWDDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYD 210

  Fly   190 FSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSI 254
            |..||:.||:.||||||||||:|..||:.||:|:|.|:.||:||||.||..|||:.|||.:|::|
  Rat   211 FEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETI 275

  Fly   255 CNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQE-YGEAAAYIQAQFEAKNK-STSK 317
            .||:.|::.||||||||.||.|||::...:...|.|:.|... ..:...::...|..|.: ...:
  Rat   276 VNNRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKRRDQQQR 340

  Fly   318 EIYCHMTCATDTNNIQFVFDAVTDVIIANNLR 349
            .:|.|.|.|.:|.||:.||..|.|.|:.:||:
  Rat   341 PLYHHFTTAINTENIRLVFRDVKDTILHDNLK 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	143/322 (44%)
Gna13	NP_001013137.1	G_alpha	29..375	CDD:214595	148/345 (43%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	50..63		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	195..203		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	218..227		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	287..294		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	347..352		2/4 (50%)