Protein Alignment Galphao and GNAZ

DIOPT Version :10

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: XP_047297302.1
• Gene: GNAZ / 2781
• HGNCID: 4395
• Length: 393
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 135/241 - (56%)
• Similarity: 168/241 - (69%)
• Gaps: 0/241 - (0%)

  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65
            |||.||:||:.||.|||.|:|:|:.:..:..::|||||||...||||||||||||||..||..|.
Human     1 MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLEA 65

  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKR 130
            .|:|:|::..|.|.||..|:||:..|.|.:.|.:|..||..:|.:..........:.|||..|:|
Human    66 CKEYKPLIIYNAIDSLTRIIRALAALRIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRR 130

  Fly   131 LWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNL 195
            ||.|.|.|.|||||:||.|.|:|.|:|:||:|:.|.||.||.:||||:|..||||||..|:||.|
Human   131 LWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIVENKFTFKEL 195

  Fly   196 NFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETT 241
            .||:.|||||||||||||||||.||||||||.:|.||..|:||..|
Human   196 TFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQT 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	120/208 (58%)
GNAZ	XP_047297302.1	G_alpha	13..>241	CDD:214595	126/227 (56%)