DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphao and gpa-13

DIOPT Version :9

Sequence 1:	NP_523684.2	Gene:	Galphao / 36104	FlyBaseID:	FBgn0001122	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001256451.1	Gene:	gpa-13 / 179746	WormBaseID:	WBGene00001675	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	307	Identity:	111/307 - (36%)
Similarity:	188/307 - (61%)	Gaps:	10/307 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 QAAKD----IKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYRPVVYSNTIQSLVAILRAMP 89
            |.::|    |:|||||:.||||:|:::|::::::..||..::...|..:|.|..:|:.|:.|||.
Worm    81 QKSEDPYSHIRLLLLGSAESGKTTVLEQVRLLYKQHFTESEYFHRRAFIYHNIFKSIKALCRAMR 145

  Fly    90 TLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKRLWQDAGVQECFSRSNEYQLNDSAK 154
            ...||:::......|:.:  :.........||::|...:|.:|.|..:|:.::|.:::.|||||.
Worm   146 MSDIQFADPINMGRAQSI--IADEHGHYGLFSKDLAEKIKHIWNDKSMQKLYARRSQFNLNDSAS 208

  Fly   155 YFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFKNLNFKLFDVGGQRSERKKWIHCFEDV 219
            |||:::|::...||:|:|:|::...|.|.|:..|.|:..|.:|:|||:|||:.:|:||...:|.:
Worm   209 YFLNNIDKINMVDYKPSERDLIMAYVPTCGVQNVIFTACNQSFQLFDIGGQKIDRRKWALQYEGI 273

  Fly   220 TAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPL 284
            .||.||:|:||||||:.||..|||:.::|.|..||..:..|..|.|.||||:.|:|.||:...||
Worm   274 DAIFFCIAISEYDQVMSEDMVTNRLDDALNLLQSISEDPAFATTPIYLFLNEIDVFCEKLSVIPL 338

  Fly   285 TICFPEYTGGQEYGEAAAYIQ-AQFEAKNKSTSKEIYCHMTC-ATDT 329
            :...|::.||.: .:|..::: ...||..| ..:.:|....| |.||
Worm   339 SKYKPDFKGGDQ-DDAIDFMENLACEALGK-RDRSLYRVYRCIAIDT 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	109/298 (37%)
gpa-13	NP_001256451.1	MRP-S32	<13..>54	CDD:287214
		G_alpha	70..397	CDD:214595	111/307 (36%)
		G-alpha	90..401	CDD:206639	109/298 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10218
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.030