Protein Alignment Galphao and gpa-2

DIOPT Version :10

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_505157.1
• Gene: gpa-2 / 179219
• WormBaseID: WBGene00001664
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 357
• Identity: 166/357 - (46%)
• Similarity: 235/357 - (65%)
• Gaps: 4/357 - (1%)

  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65
            ||..||.||:....:||.|::.:|:......:.:|||||||||.||||::|||:::....:|.|:
 Worm     1 MGLCQSEEEKVGTLKSRAIDKEIKQLQTSEERTVKLLLLGAGECGKSTVLKQMRLLTSKQYTDEE 65

  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFSEELLAAMKR 130
            ......:||:|.:..:..:::|||...:.:|:..||.|..|:....:.|.. :.|.::....:::
 Worm    66 LLTQAKLVYTNIVIEMDHLVKAMPAAGLNFSDPMREHDVHMLTLYIKDMQH-KNFQQDAADHVEK 129

  Fly   131 LWQDAGVQECFSRSNEY---QLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSF 192
            ||:|..|:..::...|.   .:.|:.:||.::|.|:..:||.|...|.|..|.||||||||.|..
 Worm   130 LWKDPVVKRLYAERKELNIRDIGDNTEYFFENLPRISKEDYHPNATDTLLLRTKTTGIVEVGFEI 194

  Fly   193 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNN 257
            |.:.|::||||||||||||||||||||.||||..|:|||::||.||||||||.||::||:||||:
 Worm   195 KKVKFRVFDVGGQRSERKKWIHCFEDVNAIIFIAALSEYNEVLFEDETTNRMIESMRLFESICNS 259

  Fly   258 KWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYIQAQFEAKNKSTSKEIYCH 322
            :||.:|:|||||||||||||||:|..:...||||.|.|.|.|..|:|:.:|||.:.:..|..|.|
 Worm   260 RWFHNTNIILFLNKKDLFEEKIKKENIHKAFPEYRGEQNYAETVAFIKTKFEALSNNPKKTFYVH 324

  Fly   323 MTCATDTNNIQFVFDAVTDVIIANNLRGCGLY 354
            .|||||||.:|.:.|:|..:||.:||...|||
 Worm   325 ETCATDTNQVQKILDSVISMIIQSNLHKSGLY 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	151/316 (48%)
gpa-2	NP_505157.1	G_alpha	13..354	CDD:214595	157/341 (46%)