Protein Alignment Galphao and gpa-14

DIOPT Version :10

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_001020966.2
• Gene: gpa-14 / 172269
• WormBaseID: WBGene00001676
• Length: 408
• Species: Caenorhabditis elegans
• Alignment Length: 374
• Identity: 120/374 - (32%)
• Similarity: 190/374 - (50%)
• Gaps: 38/374 - (10%)

  Fly     7 AEERAAAARSRL-IERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGF-TAEDFKQY 69
            |:.|..|.|..: ||:.|..:.......||:|:||...||||||.|||:|||..|| |.::..||
 Worm    45 AKLRELARRGHMEIEKELALEKKTYGSHIKILILGGPLSGKSTIFKQMQIIHVDGFKTDQELIQY 109

  Fly    70 RPVVYSNTIQSLVAILRA------MPTLSIQYSNNERESDAKMVFDVCQRMHDTEPFS----EEL 124
            |.:: .|.|:.:...|.|      :|...|::...|       :.::...|.|.  ||    .||
 Worm   110 RGLI-DNNIRDIYLQLIAGSRVVGIPLDPIEHITYE-------IDEIYAPMSDA--FSVRTISEL 164

  Fly   125 LAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVH 189
            |..:...|....:||.:.|..|::|.||.||:|::|.|:....|.|.::||:.:|..|..|..:.
 Worm   165 LEPLTEFWNSKQIQEIYKRRCEFELLDSTKYYLENLTRIADPTYLPNQEDIVHSRKATMSINSIV 229

  Fly   190 FSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHE-------------DETT 241
            |.:..::..:.||||||||||||:|.|:|...::|.:.::.|.:...|             |..:
 Worm   230 FEYTGVSLLMIDVGGQRSERKKWLHLFDDAKVVLFVIDLTGYAKRSEESRMELSRFPKFFRDVGS 294

  Fly   242 NR--MQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAYI 304
            |.  |:.:||:|:.:.......:...:||.||.|||:|.:.:..|..||.::.|...|.|.:.||
 Worm   295 NAYDMKVALKIFNEVAAASALANAVFLLFFNKVDLFKEILSQVNLQPCFSKFDGENTYEETSKYI 359

  Fly   305 QAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGL 353
            ..:| .:..|:.|.::.|.|.||:|.|::.||.|..:.:...|.:..||
 Worm   360 CEKF-IRAASSKKSVFPHFTTATNTENVKLVFRACMESVFKANAKATGL 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	110/339 (32%)
gpa-14	NP_001020966.2	G_alpha	52..406	CDD:214595	115/364 (32%)