Protein Alignment Galphao and Gna12

DIOPT Version :9

• Sequence 1: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Sequence 2: NP_034432.1
• Gene: Gna12 / 14673
• MGIID: 95767
• Length: 379
• Species: Mus musculus
• Alignment Length: 352
• Identity: 155/352 - (44%)
• Similarity: 222/352 - (63%)
• Gaps: 6/352 - (1%)

  Fly     2 GCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDF 66
            |.|:.| ||.|..|||.|:..|..:.....:.:|:||||||||||||.:|||:|||...|..:..
Mouse    25 GAARDA-EREARRRSRDIDALLARERRAVRRLVKILLLGAGESGKSTFLKQMRIIHGREFDQKAL 88

  Fly    67 KQYRPVVYSNTIQSLVAILRAMPTLSI--QYSNNERESDAKMVFDVCQRMHDTEPFSEEL-LAAM 128
            .::|..::.|.::....::.|...|.|  |:|.||:.....|.|:....: ..||.:.:| :.|:
Mouse    89 LEFRDTIFDNILKGSRVLVDARDKLGIPWQHSENEKHGMFLMAFENKAGL-PVEPATFQLYVPAL 152

  Fly   129 KRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSFK 193
            ..||:|:|::|.|||.:|:||.:|.|||||:|||:|..:|.|::||||..|..|.||||..|..|
Mouse   153 SALWRDSGIREAFSRRSEFQLGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIK 217

  Fly   194 NLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNK 258
            .:.||:.|||||||:|:||..||:.:|:|:|.|:.|||||||.||..|||:.||:.:|::|.|||
Mouse   218 KIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNK 282

  Fly   259 WFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGG-QEYGEAAAYIQAQFEAKNKSTSKEIYCH 322
            .|.:.||||||||.||..||::...:...||::.|. ....:...|:...|:.|.::.||.::.|
Mouse   283 LFFNVSIILFLNKMDLLVEKVKSVSIKKHFPDFKGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHH 347

  Fly   323 MTCATDTNNIQFVFDAVTDVIIANNLR 349
            .|.|.||.||:|||.||.|.|:..||:
Mouse   348 FTTAIDTENIRFVFHAVKDTILQENLK 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	142/317 (45%)
Gna12	NP_034432.1	G_alpha	40..377	CDD:214595	146/336 (43%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	57..70		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	198..206		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	221..230		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	290..297		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	349..354		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.830