DRSC/TRiP Functional Genomics Resources

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Protein Alignment Galphao and Galphaq

DIOPT Version :10

Sequence 1:NP_523684.2 Gene:Galphao / 36104 FlyBaseID:FBgn0001122 Length:354 Species:Drosophila melanogaster
Sequence 2:XP_061508059.1 Gene:Galphaq / 1274760 VectorBaseID:AGAMI1_001854 Length:396 Species:Anopheles gambiae


Alignment Length:396 Identity:177/396 - (44%)
Similarity:228/396 - (57%) Gaps:52/396 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGCAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAED 65
            |.|..|.|.:.....::.|||.|:.|...|.:::||||||.|||||||.:|||:|||.||::.||
Mosquito     1 MECCLSEEAKEQKRINQEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDED 65

  Fly    66 FKQYRPVVYSNTIQSLVAILRAMPTLSIQYSNNERESDAKMVFDVCQRMHDTE---PFSEELLAA 127
            .:.:..:||.|...::.:::|||..|.|.||:......|:::     |..|.|   .|....:.|
Mosquito    66 KRGFIKLVYQNIFMAMQSMIRAMDLLKILYSDPANIEHAELI-----RSVDFETVTTFEPPYVQA 125

  Fly   128 MKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSF 192
            :|.||.|||:|||:.|..||||.|||||:|.::||:.|.:|.||||||||.||.||||:|..|..
Mosquito   126 IKDLWADAGIQECYDRRREYQLTDSAKYYLMEIDRVAAPNYLPTEQDILRVRVPTTGIIEYPFDL 190

  Fly   193 KNLN-------------------------------------------FKLFDVGGQRSERKKWIH 214
            :.:.                                           |::.|||||||||:||||
Mosquito   191 EEIRFSYLSDLARIEAEDFLPTEQDILRARAPTTGILEYPFDLDSIIFRMVDVGGQRSERRKWIH 255

  Fly   215 CFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKI 279
            |||:||:|||.||:|||||:|.|.|..|||:||..||.:|....||..:|:|||||||||.||||
Mosquito   256 CFENVTSIIFLVALSEYDQILFESENENRMEESKALFKTIITYPWFQHSSVILFLNKKDLLEEKI 320

  Fly   280 RKSPLTICFPEYTGGQEYGEAA-AYIQAQFEAKNKSTSKEIYCHMTCATDTNNIQFVFDAVTDVI 343
            ..|.|...||||.|.|....|| .:|...|...|..:.|.||.|.||||||.||:.||.||.|.|
Mosquito   321 MYSHLVDYFPEYDGPQRDAIAAREFILRMFVDLNPDSEKIIYSHFTCATDTENIKLVFCAVKDTI 385

  Fly   344 IANNLR 349
            :...|:
Mosquito   386 MQTALK 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GalphaoNP_523684.2 G-alpha 34..348 CDD:206639 166/360 (46%)
GalphaqXP_061508059.1 None

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