DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphao and gna15

DIOPT Version :9

Sequence 1:	NP_523684.2	Gene:	Galphao / 36104	FlyBaseID:	FBgn0001122	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	XP_002934852.2	Gene:	gna15 / 100496529	XenbaseID:	XB-GENE-1011753	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	369	Identity:	159/369 - (43%)
Similarity:	219/369 - (59%)	Gaps:	32/369 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFKQYR 70
            |.||..|...:|.|||.||....::..:||:||||.|||||||.:|||:|||.:||:.::.|.|.
Frog    15 SEEETTALTVNREIERILKLQKERSRGEIKVLLLGTGESGKSTFIKQMRIIHGAGFSEQERKFYA 79

  Fly    71 PVVYSNTIQSLVAILRAMPTLSIQYS--NNE------RESDAKMVFDVCQRMHDTEPFSEELLAA 127
            .:|:.|.:....:::.||.||.:.||  ||:      .|.||..:          :...|..:.|
Frog    80 RLVHQNIVTCAQSLVGAMETLQVPYSIENNQINGRKISELDAFRI----------QAIEEPYVKA 134

  Fly   128 MKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHFSF 192
            :|.||.|.|:|.|:.|..|:||.||..|:|.:|:||....||||::||||.|:.||||.|..|..
Frog   135 IKNLWSDTGIQRCYERRREFQLLDSTNYYLSNLERLTQDMYQPTDEDILRIRMPTTGINEYSFPV 199

  Fly   193 KNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSICNN 257
            :|:|.::.|||||:|||:||||.||:|:|:|:..::|||||.|.|:...|||:|||.||.:|...
Frog   200 ENMNLRMVDVGGQKSERRKWIHSFENVSALIYLASLSEYDQRLEENCHDNRMKESLALFRNILEL 264

  Fly   258 KWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQEYGEAAAY------------IQAQFEA 310
            .||.:|.|||||||.||.||||..|.|...|..:.|.....|||..            |:.| :|
Frog   265 PWFQETPIILFLNKTDLLEEKIAFSDLANYFHRFKGPCRDAEAAKQFILDNYKEIFNKIRKQ-DA 328

  Fly   311 KNKSTSK-EIYCHMTCATDTNNIQFVFDAVTDVIIANNLRGCGL 353
            ..|...| ::|.|.||||||:||:.||:.|.:.::...|...|:
Frog   329 SGKDDLKHKVYHHFTCATDTDNIRKVFNNVKEAVLVKYLMDFGI 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	147/334 (44%)
gna15	XP_002934852.2	G-alpha	43..363	CDD:206639	147/330 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930