DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphao and gna13

DIOPT Version :9

Sequence 1:	NP_523684.2	Gene:	Galphao / 36104	FlyBaseID:	FBgn0001122	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001120411.1	Gene:	gna13 / 100145489	XenbaseID:	XB-GENE-6257775	Length:	377	Species:	Xenopus tropicalis

Alignment Length:	356	Identity:	153/356 - (42%)
Similarity:	218/356 - (61%)	Gaps:	10/356 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 CAQSAEERAAAARSRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDFK 67
            |..::.|.....:|:.|:|.|..:.....:.:|:||||||||||||.:|||:|||...|.....:
Frog    18 CVLTSREAEQQRKSKEIDRCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDLRAKE 82

  Fly    68 QYRPVVYSNTIQSLVAILRAMPTLSIQYSN--NERESDAKMVFD-----VCQRMHDTEPFSEELL 125
            ::|..:|||.|:.:..::.|...|.|.:.:  |::..:..|.||     |.|.|.:|:.|...||
Frog    83 EFRATIYSNVIKGIRVLVDAREKLHIPWGDPANQKHGEVMMAFDTRSAMVAQGMVETQVFVSHLL 147

  Fly   126 AAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEVHF 190
             :::.||.|.|:|..:.|..|:||.:|.|||||:||:||.|||.|::||||..|..|.||.|..|
Frog   148 -SIRSLWADTGIQTAYDRRREFQLGESVKYFLDNLDKLGDKDYLPSQQDILLARRPTKGIHEYDF 211

  Fly   191 SFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDSIC 255
            ..||:.||:.||||||||||:|..||:.||:|:|.|:.|||||||.||..|||:.|||.:|::|.
Frog   212 EIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEYDQVLMEDRQTNRLTESLNIFETIV 276

  Fly   256 NNKWFTDTSIILFLNKKDLFEEKIRKSPLTICFPEYTGGQE-YGEAAAYIQAQFEAKNK-STSKE 318
            ||:.|::.||||||||.||.|||:|...:...|.::.|... ..:...::...|..|.: ...|.
Frog   277 NNRVFSNVSIILFLNKTDLLEEKVRIVSIKDYFADFEGDPHCLEDVQKFLVNCFRNKRRDQQQKP 341

  Fly   319 IYCHMTCATDTNNIQFVFDAVTDVIIANNLR 349
            :|.|.|.|.:|.||:.||..|.|.|:.:||:
Frog   342 LYHHFTTAINTENIRLVFRDVKDTILHDNLK 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	145/322 (45%)
gna13	NP_001120411.1	G_alpha	29..375	CDD:214595	151/345 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930