DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12895 and SDHAF2

DIOPT Version :9

Sequence 1:NP_001260868.1 Gene:CG12895 / 36103 FlyBaseID:FBgn0033523 Length:156 Species:Drosophila melanogaster
Sequence 2:NP_060311.1 Gene:SDHAF2 / 54949 HGNCID:26034 Length:166 Species:Homo sapiens


Alignment Length:158 Identity:71/158 - (44%)
Similarity:95/158 - (60%) Gaps:10/158 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 VSTV--GRRLQLPMMAQSRLASNLDKTEY------TTPGEIVDYDDPPHLPVPEYPVRPDEPLET 63
            ||||  ...|.|.:...|.|:..|..|.:      .:|.:  ...|...:|:|.:..|.||.:||
Human     3 VSTVFSTSSLMLALSRHSLLSPLLSVTSFRRFYRGDSPTD--SQKDMIEIPLPPWQERTDESIET 65

  Fly    64 RKQRLLYQSRKRGMLENDLLLSTFVAKHLKDFNAEQTAEYDQLINGVSNDWDIFYWATDTKPTPP 128
            ::.||||:|||||||||.:|||.|..:||:....:|...||:|||..||||||:||||:.||.|.
Human    66 KRARLLYESRKRGMLENCILLSLFAKEHLQHMTEKQLNLYDRLINEPSNDWDIYYWATEAKPAPE 130

  Fly   129 QFDTEIMRLLKEHVKNHEKVQRIRQPDL 156
            .|:.|:|.||::..||..|.||:|.|||
Human   131 IFENEVMALLRDFAKNKNKEQRLRAPDL 158

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12895NP_001260868.1 Sdh5 65..138 CDD:281870 41/72 (57%)
SDHAF2NP_060311.1 Sdh5 67..140 CDD:397843 41/72 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165142943
Domainoid 1 1.000 98 1.000 Domainoid score I7190
eggNOG 1 0.900 - - E1_COG2938
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H32370
Inparanoid 1 1.050 133 1.000 Inparanoid score I4606
Isobase 1 0.950 - 0 Normalized mean entropy S1158
OMA 1 1.010 - - QHG48810
OrthoDB 1 1.010 - - D1492851at2759
OrthoFinder 1 1.000 - - FOG0003243
OrthoInspector 1 1.000 - - otm40823
orthoMCL 1 0.900 - - OOG6_102226
Panther 1 1.100 - - O PTHR12469
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1299
SonicParanoid 1 1.000 - - X3172
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1716.750

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