Protein Alignment CG12896 and MDS3

DIOPT Version :10

• Sequence 1: NP_610584.2
• Gene: CG12896 / 36101
• FlyBaseID: FBgn0033521
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_011318.2
• Gene: MDS3 / 852678
• SGDID: S000003165
• Length: 1487
• Species: Saccharomyces cerevisiae
• Alignment Length: 311
• Identity: 58/311 - (18%)
• Similarity: 99/311 - (31%)
• Gaps: 108/311 - (34%)

  Fly     4 GQTVPNFEADTTKGP-------IKFHEWQGNSWVVLFSHPADFTPVC----TTELGRIAVHQPEF 57
            |:.:.:||..|::|.       :....| |..:.:|.|.  .:|.||    ||:.....:.....
Yeast   540 GKPLSDFEFITSEGDSIGIPCYLLRKRW-GRYFDMLLSQ--SYTKVCADYETTDTQSTLIKFSPH 601

  Fly    58 AKRNTKCLAHSVDALNSHVDWVNDIKSYCLDIPGDFPYPIIA----------------------- 99
            :.||:.........|:|         |..||...:..:||.|
Yeast   602 SSRNSSKAVRQEGRLSS---------SGSLDNYFEKNFPIFARTSVSEAQNTQPQVANADAKAPN 657

  Fly   100 ------DPTRDLAVTLGML-------DEEQKKDPEVGKTI-RALFIISPDHKVRLSMFYPMSTG- 149
                  :|:...:..|...       |||..:||...|.: ::..|..|..|...|.....|.|
Yeast   658 TPSTSDEPSSSSSSDLYSTPHYQRNNDEEDDEDPVSPKPVSKSNSIYRPIRKTESSSTTSSSNGM 722

  Fly   150 -------------RNVDEILRTIDSLQLTDRLK--VVATPA------------------------ 175
                         .|.:.:|.:..|||...|.:  :::.|:
Yeast   723 IFRVPFKEKAAVTSNTEALLESNLSLQELSRRRSSLMSIPSGELLRSSISEAEHQRRASHPLTSS 787

  Fly   176 -----NWTP-GTKVMILPSVTDDEAHK-LFPKGFDKVSMPSGVNYVRTTEN 219
                 :.|| |.::..|...|....|. |.|:.|.: |..|.::||.::.:
Yeast   788 PLFEDSGTPCGKQLQQLQQHTIQNPHNHLSPRRFSR-SARSSISYVSSSSD 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12896	NP_610584.2	PRX_1cys	3..218	CDD:239314	58/308 (19%)
MDS3	NP_011318.2	NanM	<156..>263	CDD:442289
		KELCH repeat	160..210	CDD:276965
		KELCH repeat	216..263	CDD:276965