DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12896 and prdx-6

DIOPT Version :9

Sequence 1:	NP_610584.2	Gene:	CG12896 / 36101	FlyBaseID:	FBgn0033521	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_741287.1	Gene:	prdx-6 / 176837	WormBaseID:	WBGene00021401	Length:	231	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	93/226 - (41%)
Similarity:	128/226 - (56%)	Gaps:	10/226 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLGQTVPN--FEADTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNTK 63
            |:||.||||  ||.|..|.. ..|.:.|..|::||||||||||||||||..:....|||.||:.:
Worm     1 MKLGDTVPNFTFETDLRKNQ-TLHNYIGEQWLMLFSHPADFTPVCTTELAELVKLAPEFRKRHVQ 64

  Fly    64 CLAHSVDALNSHVDWVNDIKSYC--LDIPGDFPYPIIADPTRDLAVTLGMLDEEQKKDPEVGKTI 126
            .||.|:|:..:|.||..||.|..  .:.....|:.||||..|.:...|||:|.::.....:..:.
Worm    65 ILAISIDSSETHRDWAKDINSVAQLSNCGSHLPFEIIADTDRSICTELGMIDPDEMNSEGICLSA 129

  Fly   127 RALFIISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMILPSVTD 191
            ||:.:..||.|::..:.||.:.|||..||||.:|.:||..:.. |||||||..|..|:..||::.
Worm   130 RAVMLFGPDKKLKSKILYPATFGRNFVEILRMVDGVQLGTKAP-VATPANWIAGDNVIAQPSLSQ 193

  Fly   192 DEA-HKLFPKGFDK---VSMPSGVNYVRTTE 218
            :.. .:|.....||   |.:|||.:|:|..|
Worm   194 ERVIQELCGGDPDKCKTVPLPSGKSYLRVIE 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12896	NP_610584.2	AhpC	1..194	CDD:223527	83/196 (42%)
CG12896	NP_610584.2	PRX_1cys	3..218	CDD:239314	91/222 (41%)
prdx-6	NP_741287.1	PRX_1cys	3..221	CDD:239314	90/219 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158550
Domainoid	1	1.000	124	1.000	Domainoid score	I3407
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I2532
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60653
OrthoDB	1	1.010	-	-		D1129256at2759
OrthoFinder	1	1.000	-	-		FOG0002615
OrthoInspector	1	1.000	-	-		otm14762
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	O	PTHR43503
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2241
SonicParanoid	1	1.000	-	-		X1721
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840