DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG12896 and Prdx6

DIOPT Version :9

Sequence 1:NP_610584.2 Gene:CG12896 / 36101 FlyBaseID:FBgn0033521 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_031479.1 Gene:Prdx6 / 11758 MGIID:894320 Length:224 Species:Mus musculus


Alignment Length:216 Identity:114/216 - (52%)
Similarity:149/216 - (68%) Gaps:2/216 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LGQTVPNFEADTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNTKCLAH 67
            ||...|||||:||.|.|:||::.|:||.:|||||.||||||||||||.|...|||||||.|.:|.
Mouse     7 LGDEAPNFEANTTIGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIAL 71

  Fly    68 SVDALNSHVDWVNDIKSYCLDIPGD-FPYPIIADPTRDLAVTLGMLDEEQKKDPEVGKTIRALFI 131
            |:|::..|:.|..||.:|..:.|.: .|:|||.|..||||:.|||||..:|....:..|.|.:||
Mouse    72 SIDSVEDHLAWSKDINAYNGETPTEKLPFPIIDDKGRDLAILLGMLDPVEKDANNMPVTARVVFI 136

  Fly   132 ISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMILPSVTDDEAHK 196
            ..||.|::||:.||.:||||.|||||.:||||||. .|.||||.:|..|..||::|:::::||.:
Mouse   137 FGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTG-TKPVATPVDWKKGESVMVVPTLSEEEAKQ 200

  Fly   197 LFPKGFDKVSMPSGVNYVRTT 217
            .||||.....:|||..|:|.|
Mouse   201 CFPKGVFTKELPSGKKYLRYT 221

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12896NP_610584.2 AhpC 1..194 CDD:223527 102/191 (53%)
PRX_1cys 3..218 CDD:239314 114/216 (53%)
Prdx6NP_031479.1 PRX_1cys 7..222 CDD:239314 114/216 (53%)
Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000250|UniProtKB:O35244 31..40 5/8 (63%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167835448
Domainoid 1 1.000 151 1.000 Domainoid score I4332
eggNOG 1 0.900 - - E1_COG0450
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG60653
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0002615
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100111
Panther 1 1.100 - - O PTHR43503
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2241
SonicParanoid 1 1.000 - - X1721
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1211.740

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