Protein Alignment CG12896 and Prdx6

DIOPT Version :10

• Sequence 1: NP_610584.2
• Gene: CG12896 / 36101
• FlyBaseID: FBgn0033521
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_031479.1
• Gene: Prdx6 / 11758
• MGIID: 894320
• Length: 224
• Species: Mus musculus
• Alignment Length: 216
• Identity: 114/216 - (52%)
• Similarity: 149/216 - (68%)
• Gaps: 2/216 - (0%)

  Fly     3 LGQTVPNFEADTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNTKCLAH 67
            ||...|||||:||.|.|:||::.|:||.:|||||.||||||||||||.|...|||||||.|.:|.
Mouse     7 LGDEAPNFEANTTIGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKLIAL 71

  Fly    68 SVDALNSHVDWVNDIKSYCLDIPGD-FPYPIIADPTRDLAVTLGMLDEEQKKDPEVGKTIRALFI 131
            |:|::..|:.|..||.:|..:.|.: .|:|||.|..||||:.|||||..:|....:..|.|.:||
Mouse    72 SIDSVEDHLAWSKDINAYNGETPTEKLPFPIIDDKGRDLAILLGMLDPVEKDANNMPVTARVVFI 136

  Fly   132 ISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMILPSVTDDEAHK 196
            ..||.|::||:.||.:||||.|||||.:||||||. .|.||||.:|..|..||::|:::::||.:
Mouse   137 FGPDKKLKLSILYPATTGRNFDEILRVVDSLQLTG-TKPVATPVDWKKGESVMVVPTLSEEEAKQ 200

  Fly   197 LFPKGFDKVSMPSGVNYVRTT 217
            .||||.....:|||..|:|.|
Mouse   201 CFPKGVFTKELPSGKKYLRYT 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12896	NP_610584.2	PRX_1cys	3..218	CDD:239314	114/216 (53%)
Prdx6	NP_031479.1	PRX_1cys	7..222	CDD:239314	114/216 (53%)
		Required and sufficient for targeting to lysosomes and lamellar bodies. /evidence=ECO:0000250|UniProtKB:O35244	31..40		5/8 (63%)