Protein Alignment AQP4 and Eglp1

DIOPT Version :10

• Sequence 1: NP_001304313.1
• Gene: AQP4 / 361
• HGNCID: 637
• Length: 352
• Species: Homo sapiens
• Sequence 2: NP_611810.1
• Gene: Eglp1 / 37736
• FlyBaseID: FBgn0034882
• Length: 238
• Species: Drosophila melanogaster
• Alignment Length: 219
• Identity: 56/219 - (25%)
• Similarity: 107/219 - (48%)
• Gaps: 10/219 - (4%)

Human    41 EFLAMLIFVLLS-LGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAM 104
            ||.|..:.:||. :|.:.|.||..|     .::.|:.:||::..::..||.:||.|.||.::::.
  Fly    14 EFSATALLILLGCMGDSTNQGGESK-----FLVASVHYGLTVMVVMHVFGFVSGAHSNPCISISC 73

Human   105 VCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVG----GLGVTMVHGNLTAGHGLLVELI 165
            .....|::...:.|:..|..||.:|..:|..:.|..:|.    |:.:......|:....:::|.:
  Fly    74 YLMGYIALEVMMMYVVCQMAGAFLGYFLLMQLLPKELVDKSKPGICLVQPMDTLSTYQVVIIECL 138

Human   166 ITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENH 230
            :|..||....:..|.:......|:|:.:|..|.......|..||||||||::..||:..|:..:.
  Fly   139 LTAVLVLGWCSLWDVRNGRFLDSVAIRMGLLVIACSFAGIQLTGASMNPAKTLVPAIFYGSPNSV 203

Human   231 WIYWVGPIIGAVLAGGLYEYVFCP 254
            .:...|.|:.|::...::.:.:.|
  Fly   204 LMQLTGQILAAIMVPFVWNHAYTP 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP4	NP_001304313.1	MIP	31..248	CDD:395174	55/211 (26%)
Eglp1	NP_611810.1	GlpF	14..197	CDD:440345	51/187 (27%)