DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prx2540-2 and prdx6

DIOPT Version :9

Sequence 1:	NP_523683.1	Gene:	Prx2540-2 / 36098	FlyBaseID:	FBgn0033518	Length:	220	Species:	Drosophila melanogaster
Sequence 2:	NP_957099.1	Gene:	prdx6 / 393778	ZFINID:	ZDB-GENE-040426-1778	Length:	222	Species:	Danio rerio

Alignment Length:	221	Identity:	116/221 - (52%)
Similarity:	150/221 - (67%)	Gaps:	12/221 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LGQTVPNFEADTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNTKCLAH 67
            ||...||||||||.|.|||||:.||||.:|||||.||||||||||.|.|....||.||:.|.:|.
Zfish     6 LGDVFPNFEADTTIGKIKFHEFLGNSWGILFSHPRDFTPVCTTELARAAKLHEEFKKRDVKMIAL 70

  Fly    68 SVDALNSHVDWVNDI------KSYCLDIPGDFPYPIIADPTRDLAVSLGMLDEEQKKDPEVGKTI 126
            |:|::..|..|..||      |:.|     ..|:|||||..|:|:|.|||||.:::....:..|.
Zfish    71 SIDSVEDHRKWSEDILAFNQDKACC-----PMPFPIIADDKRELSVLLGMLDPDERDKDGMPLTA 130

  Fly   127 RALFIISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMILPTVTD 191
            |.:|::.||.:::||:.||.:||||.|||||.:|||||| ..|.||||.:|.||.:||::|:::|
Zfish   131 RCVFVVGPDKRLKLSILYPATTGRNFDEILRVVDSLQLT-ATKKVATPVDWKPGQEVMVIPSLSD 194

  Fly   192 EEAHKLFPKGFDKVSMPSGVNYVRTT 217
            |||:||||.||....:|||..|:|.|
Zfish   195 EEANKLFPAGFTLKEVPSGKKYIRYT 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prx2540-2	NP_523683.1	AhpC	1..194	CDD:223527	102/196 (52%)
Prx2540-2	NP_523683.1	PRX_1cys	3..218	CDD:239314	116/221 (52%)
prdx6	NP_957099.1	AhpC	5..199	CDD:223527	104/198 (53%)
prdx6	NP_957099.1	PRX_1cys	6..221	CDD:239314	116/221 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11444
eggNOG	1	0.900	-	-		E1_COG0450
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60653
OrthoDB	1	1.010	-	-		D1129256at2759
OrthoFinder	1	1.000	-	-		FOG0002615
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100111
Panther	1	1.100	-	-	O	PTHR43503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1721
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.790