Protein Alignment Ir47a and glr-8

DIOPT Version :10

• Sequence 1: NP_610580.1
• Gene: Ir47a / 36095
• FlyBaseID: FBgn0033515
• Length: 593
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 480
• Identity: 88/480 - (18%)
• Similarity: 168/480 - (35%)
• Gaps: 93/480 - (19%)

  Fly   147 TLKTRRFYPFPQPKVQVIDKPFEEKEIYPAL---WRNFMGKNAIAVPDLVPPRSFNSFDPKTGHR 208
            ||...:.:...:.|.:.:      |.:.||:   :.|::..:..||.|       ..:.|
 Worm    47 TLSNEKHFSLSEMKGRTL------KMVVPAIEPPYVNYVNFSDAAVTD-------KGYGP----- 93

  Fly   209 RESGSIYNVFKAFTQRYNITMLL------KWPLIRNTTQEEIIGKSVRGEIDLPITGQLISF-RH 266
               |.:..:.|...:|.|:|..:      .|....|.:.....|:.||||:||...|.::.: |.
 Worm    94 ---GVVMEILKEIGKRLNLTYEILPALGSTWGEYLNGSWTGAFGQLVRGEVDLLAGGAIMEYDRS 155

  Fly   267 PNGSRSQPL-LGMTALSIAVPCGPELPMFDRFFLFYGLATPIT-----ITGYYVLLNTIEIILGT 325
            .....:.|. ...|.:.|.   .||....|...:   :..|.:     ||...:|::.:..::.|
 Worm   156 VIADLTYPFQFEPTGIMIR---SPEKYEDDTLLI---VTEPFSWEVWVITAAVILISGVIFLVMT 214

  Fly   326 LSDRIKRHPRRKKILNLVLNLRV-FSCILSLPTPQGNRLRSVK--------GQLTMVMSITGLIL 381
               .|.|....:..:....::.| ||..:....|:..|..|.:        ..:|:..:.||.::
 Worm   215 ---NIIRKVYEEMTVTPFESIWVFFSIFVQQGLPEQPRSWSCRVLVALWWLASITLSATFTGSLV 276

  Fly   382 SCIVAAQTSTILTMKPQYRHIKNFQEL-SDSNITVVCNHLNYLTIKQQMDPKFMAKFMQNIW--- 442
            :.....:|:.      .:::|.....| ......:|.:..::  .:.:|..:......:::|
 Worm   277 ALFAVDKTNV------PFQNIDQLVRLVKQGKFEIVMDENSF--TRTEMIARSKLPVYRDLWHEM 333

  Fly   443 -------IVNSIEQMKMIFDLNTSYAYQTFSYKKDPFTLLQMHTTRKAFCRTPGLDLVSGL--AY 498
                   .||.|.:.......|..||.      ..|...|..:    |:.....:....|:  .|
 Worm   334 IVNHKVKYVNGIARGVAFVRANPGYAL------LGPMATLNFY----AYSDCKVILFNDGILPVY 388

  Fly   499 TAV-LEKNSIYALALQDYTLKAFSAGLVYYWAEESIRDLISTVGRTQFEKL-PIVIGYQS-LKLQ 560
            .:: |.|||||:........:....|....|    |.|..|.|...:..:. ...||.:| |.|:
 Worm   389 LSIPLVKNSIYSPYFSTKIREMVERGFTQKW----IADYRSYVAMQKINECNSTTIGPKSYLDLK 449

  Fly   561 DYNVCWKILLIGGALAFCVFIVEVV 585
            .....:.:.|.|..|...:|:.|.:
 Worm   450 RAQGAFWVFLGGAGLGLALFVGEFI 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir47a	NP_610580.1	None
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	73/413 (18%)