Protein Alignment Ndg and arr

DIOPT Version :10

• Sequence 1: NP_610575.1
• Gene: Ndg / 36089
• FlyBaseID: FBgn0026403
• Length: 1350
• Species: Drosophila melanogaster
• Sequence 2: NP_524737.2
• Gene: arr / 44279
• FlyBaseID: FBgn0000119
• Length: 1678
• Species: Drosophila melanogaster
• Alignment Length: 375
• Identity: 113/375 - (30%)
• Similarity: 179/375 - (47%)
• Gaps: 76/375 - (20%)

  Fly   997 EEQNCLNNPTLCDMNAQCR-----STNS-GLVCVCNQGF-------FGNGSLCQERQHQDSDFLI 1048
            |:..|.:|      |..|.     :||| |..|.|..|.       ..|||         .:.:.
  Fly   357 EDNPCAHN------NGNCSHLCLLATNSQGFSCACPTGVKLISANTCANGS---------QEMMF 406

  Fly  1049 VSQGVMIARVPLNGRNVR----PISVAQMAIGLDKDCVEGRVYWGDISTKKIVSTKYDGTDLRPF 1109
            :.|...|:::.|:..:..    |:...:.||.:|.|.||..:||.|:.|..|.....|||.:..|
  Fly   407 IVQRTQISKISLDSPDYTIFPLPLGKVKYAIAIDYDPVEEHIYWSDVETYTIKRAHADGTGVTDF 471

  Fly  1110 ITTDIESPEGIAIDVISRRLYWADSAKDTIEVASLDDPSLRAVIINKQLVNPRGIAVDPYREKLF 1174
            :|:::..|:|:|:|.::|.|||.|:..|.|||..||. :.|.|:|.:.|..||.|||.|....:|
  Fly   472 VTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDG-TARKVLIYEHLEEPRAIAVAPSLGWMF 535

  Fly  1175 WSDWDRESPKIEMSNLDGTGRELLLGKDDVTLPNSLVVLENSGEVCYADAGTKKVEC--IEPQNR 1237
            ||||:...||:|.::|||:.|.:|: .:::..||.:.:...:..:.:.|..|.|:|.  ::...|
  Fly   536 WSDWNERKPKVERASLDGSERVVLV-SENLGWPNGIALDIEAKAIYWCDGKTDKIEVANMDGSGR 599

  Fly  1238 QIRTISNELSYPFGITFTHDQFYWTDWTTKKVEIVDSLGARQTPIQPPFFGSHKMYG---MTVVE 1299
            :: .||:.|.:.||::...|..|||||..:.::                 .:||:.|   :.||:
  Fly   600 RV-VISDNLKHLFGLSILDDYLYWTDWQRRSID-----------------RAHKITGNNRIVVVD 646

  Fly  1300 QHCPQY-------------QSPCQISNGGCTDSRLCLVNRQAPSGKSCKC 1336
            |: |..             |:.|.:.||||  |.||| ||  |....|:|
  Fly   647 QY-PDLMGLKVTRLREVRGQNACAVRNGGC--SHLCL-NR--PRDYVCRC 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndg	NP_610575.1	NIDO	108..262	CDD:214712
		EGF_3	285..320	CDD:463759
		G2F	322..549	CDD:214774
		EGF_CA	591..622	CDD:429571
		EGF_3	797..828	CDD:463759
		EGF_3	836..873	CDD:463759
		EGF_3	963..995	CDD:463759
		EGF_3	1001..1036	CDD:463759	14/47 (30%)
		NHL	1074..>1254	CDD:302697	66/181 (36%)
		NHL repeat	1074..1112	CDD:271320	15/37 (41%)
		LY	1107..1145	CDD:214531	15/37 (41%)
		NHL repeat	1117..1156	CDD:271320	18/38 (47%)
		LY	1152..1195	CDD:214531	20/42 (48%)
		NHL repeat	1161..1202	CDD:271320	19/40 (48%)
		NHL repeat	1210..1244	CDD:271320	6/35 (17%)
arr	NP_524737.2	LY	162..201	CDD:214531
		NHL	168..503	CDD:302697	46/160 (29%)
		NHL repeat	172..237	CDD:271320
		LY	252..293	CDD:214531
		NHL repeat	261..298	CDD:271320
		NHL repeat	303..339	CDD:271320
		NHL repeat	341..419	CDD:271320	17/76 (22%)
		NHL repeat	428..476	CDD:271320	17/47 (36%)
		LY	472..511	CDD:214531	16/39 (41%)
		NHL repeat	477..503	CDD:271320	11/25 (44%)
		Ldl_recept_b	534..574	CDD:459654	15/40 (38%)
		LY	558..599	CDD:214531	7/41 (17%)
		LY	600..641	CDD:214531	14/58 (24%)
		FXa_inhibition	668..703	CDD:464251	14/28 (50%)
		YncE	<736..886	CDD:442618
		LY	776..818	CDD:214531
		LY	905..946	CDD:214531
		FXa_inhibition	973..1010	CDD:464251
		YncE	<1047..1191	CDD:442618
		LDLa	1319..1362	CDD:238060
		LDLa	1365..1399	CDD:238060
		LDLa	1399..1433	CDD:197566