Protein Alignment CG12909 and LYAR

DIOPT Version :9

• Sequence 1: NP_610573.1
• Gene: CG12909 / 36087
• FlyBaseID: FBgn0033507
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001139197.1
• Gene: LYAR / 55646
• HGNCID: 26021
• Length: 379
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 111/390 - (28%)
• Similarity: 178/390 - (45%)
• Gaps: 124/390 - (31%)

  Fly     1 MVFFTCNICGESVKKPAVEKHYQTRCRGKDKNVSCMDCLKDFYGEEYVAHIKCISEAQKYASQSQ 65
            |||||||.|||||||..||||... ||..: .:||:||.|||:|::|..|:|||||.|||.  .:
Human     1 MVFFTCNACGESVKKIQVEKHVSV-CRNCE-CLSCIDCGKDFWGDDYKNHVKCISEDQKYG--GK 61

  Fly    66 GFAAKEPRNKNAQKQESWMDIIRSILDSSEYNLTPAVRSAFQKLQSVDNVPRKKAKFENFVGNCM 130
            |:..|  .:|...||::|:..|..::  ...|::|.||...:::.:.||||||||||:|::.|.:
Human    62 GYEGK--THKGDIKQQAWIQKISELI--KRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNSL 122

  Fly   131 RMPRNQA--TQVWDILEKELN------------------------------KMKEA--KQAELAR 161
            :: .|::  .|||:|..:..|                              |:|:|  :|.|:.:
Human   123 KV-HNESILDQVWNIFSEASNSEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKK 186

  Fly   162 AKAEKIAEIQQKQKAEVEE------------EAPPKKKAKVETTEDAAAEET--SNG-------- 204
            .|.|:..|.|:|:|.|.:|            :.|.|:|...|...:|..||.  :||
Human   187 NKRERKEERQKKRKREKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKK 251

  Fly   205 --------------------------VTSD---------------------------FDWAAQLT 216
                                      |.:|                           |:|...:
Human   252 KKQRKDSASEEEARVGAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTI- 315

  Fly   217 KIVTKQA--DGIFLEKLRKKLLKKYAKHLSVEDLNEKQAKKFQKRFDKQLKLADSLEVEGEIVKI 279
            |.:.|||  :.|.::|||||:|   |::.:|.|.:.:..::....|:|::....:.::..:.||:
Human   316 KAILKQAPDNEITIKKLRKKVL---AQYYTVTDEHHRSEEELLVIFNKKISKNPTFKLLKDKVKL 377

  Fly   280  279
            Human   378  377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12909	NP_610573.1	zf-LYAR	33..60	CDD:285943	16/26 (62%)
LYAR	NP_001139197.1	zf-LYAR	31..58	CDD:312357	16/26 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..307		24/145 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152965
Domainoid	1	1.000	63	1.000	Domainoid score	I10307
eggNOG	1	0.900	-	-		E1_KOG2186
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	132	1.000	Inparanoid score	I4630
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005214
OrthoInspector	1	1.000	-	-		oto91159
orthoMCL	1	0.900	-	-		OOG6_106568
Panther	1	1.100	-	-	LDO	PTHR13100
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3728
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.750