Protein Alignment CAP and sh3d19

DIOPT Version :9

• Sequence 1: NP_001369075.1
• Gene: CAP / 36084
• FlyBaseID: FBgn0033504
• Length: 2568
• Species: Drosophila melanogaster
• Sequence 2: XP_009289295.1
• Gene: sh3d19 / 553811
• ZFINID: ZDB-GENE-050522-481
• Length: 963
• Species: Danio rerio
• Alignment Length: 1106
• Identity: 216/1106 - (19%)
• Similarity: 360/1106 - (32%)
• Gaps: 372/1106 - (33%)

  Fly  1678 RISKIEDEHDHSAVDKATISDEFLDRVKERRHKLSMPADSDWE-----SGAESQPQPAAQSQPES 1737
            |.|...::..:.:|.:...|.:..:|.|..|.::|....|..:     :.|::.|||....:.
Zfish     5 RCSDGSEDFSNVSVTRRRDSTDRSERSKPERLQISQGPLSSIKAAIKRTSAKALPQPVCSRER-- 67

  Fly  1738 DVEAPPVRILEGQAEA---------------------------NLRQLPRHLREFAKFSTSEQLP 1775
              ..|.:.||..:..|                           ...|||....:..|..|.||:.
Zfish    68 --RRPEITILSAEPFAATWYPVPSGRFSSTAFTTQPVWSENALTSAQLPPSYEQVIKEKTQEQVT 130

  Fly  1776 DGAQMERHEEQERREEATDNAHSSATKKTSIVKTYKVSRLPPSVQGEFPGQFSGGNRGRLYRERS 1840
            ..:...||.........||:...:.|...|..          |:|                 :..
Zfish   131 TPSPSPRHSYTTTIATQTDSLEENVTSPDSCT----------SLQ-----------------QNQ 168

  Fly  1841 QTARLVSHNIPLELTSNHSSSPDSDFNPGCGSSPAPGSSTQSSIPSLVQSPT--------PAPPP 1897
            |.|.||...|          .|.....| |...|....:|:||..:.:..||        |.|.|
Zfish   169 QPAVLVKQPI----------KPPRPTLP-CKPKPLLQETTRSSTSTFISQPTVDQTPIQRPVPQP 222

  Fly  1898 --PIEPLNPSSSTAGGILGTALLL-----GLSLLTAW----NKFIYKVKHEYMSEPETGSDRPRK 1951
              ..:||:||:...|   .|.:.|     .:||:..:    .|::.::.....|||:
Zfish   223 RTKFKPLSPSNQVTG---QTLIPLQDSCDTISLVETFESHSGKYLKELVDVLSSEPQ-------- 276

  Fly  1952 MAQLGRRQYDGIGPVTNDGMPIILRSE-----VKEPHQHEWYKRLYQTIHKQKNGDDFVIRYKCP 2011
             ::|.       .||.|.|....|.:|     :...|.....:...|....|...::.......|
Zfish   277 -SELS-------NPVNNQGEQTNLTNENQIENMTFHHSDRNIRSRIQAFESQAATENDAASVPFP 333

  Fly  2012 RAR------------PSYKSNGYVSEPEPNYDSDYSTVRYR------TQNPH-----------RV 2047
            |.|            ||......|.:|:....|.:.:..|.      |..|.           |.
Zfish   334 RPRKIGAKPPILAPKPSIAPRPSVIKPKEEPFSQFDSHLYEELDMEPTPAPRPQLFKKPSLDSRE 398

  Fly  2048 QSVS------------SAVNVRNL-NQDEKLY--GTMPNPIKSAQN----SYKNQPGRIENYTTG 2093
            :|.|            |.|..:|: :|||::.  |.:| |:|.:::    :..|....:.:.|:.
Zfish   399 ESDSQPFFKTALTSRPSLVKHKNVYSQDEEVVVKGPIP-PLKPSKDLLNANNHNSTALLPDLTSA 462

  Fly  2094 HSSVSEKEKKEWWDEVMDIFNGNLEQSKLSPL------YTEGNLSRA------------------ 2134
            .:.:|.           |..:.::..|...|:      |..||....
Zfish   463 VNVLSN-----------DYVDTSINHSPTKPVRQGGFSYMGGNTQAVTRRPTVIRVPSKTDKISA 516

  Fly  2135 ---------------LAKESGYTSDSNLVFRKKEVPVSSPLSPVEQKQAYKSL-------QAG-G 2176
                           :.|..|.|......||:....|||.:|...:....|.|       :.| |
Zfish   517 FSDSEEAVEFPPPLPVQKAVGSTPTPAKAFRQDPFNVSSDMSIPPRPSGGKVLPPRPPPAKTGPG 581

  Fly  2177 EPPL------------LGFRKPAPEKP---------RDLDPNAPPIPPQP--------------P 2206
            .||.            .||.:.||.|.         |......|.:||:|              |
Zfish   582 RPPPPQTNNSQRRPSDSGFSQIAPSKQQPSQWQQQNRRASKKGPALPPRPNPGHRLYNKYTLEVP 646

  Fly  2207 VKGLSSYDFPYSTDTVDGSDV-NIHFKTPIRHEQRQNLSEEELAIR-------------QAEHMQ 2257
             .|::.:|:       :||:. .:.|:   ::|....|  |||..|             |..||
Zfish   647 -HGIAEFDY-------NGSNTGELSFQ---KNEVLVLL--EELDSRTFECQAGNTKGTVQKSHM- 697

  Fly  2258 KLYHEERRRKYLQELQDMNSRRHTDNFTPSQKSPIALNRYDDFPTDVTLKSLVG--PKTVARALF 2320
                     |.:..|.|::|     |..|.:.|              :.:.:.|  ......||:
Zfish   698 ---------KIITPLTDLSS-----NSLPQKTS--------------SFRGMGGNAGSLQVEALY 734

  Fly  2321 NFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPS------KR 2379
            :|......||:.:.||.:....|:|.:||.|......|..|.:||:::|:.....|:      .:
Zfish   735 DFTPAGPGELALKAGDVVSNVEQLDDDWYMGTCRNATGFFPINYVKVLSKPNIYAPAFRNEWKNK 799

  Fly  2380 PSEGQAR-----AKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTD 2439
            ||....|     |:::|:.:.|.|||..:.:::.|...:...|..|::....||||.::|||:.|
Zfish   800 PSPETVRGPRCVARFDFEGEQGDELSFFEDDVIQLKEYLGEEWARGEVNGHVGIFPLNFVEVIED 864

  Fly  2440 IGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGI----LKETRTLHKT 2500
            :                      |::.|.::               .||.|    :..:.|....
Zfish   865 L----------------------PSVPVQKS---------------APNKIALPGMASSSTQSSY 892

  Fly  2501 DALHVDTSSEPLAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYV 2565
            .|...:::....|. |||.:..:..::|...:||.:.|....||.|:.|  :..|..|.||..:|
Zfish   893 RASEAESNGAEWAV-ALYDFTAETEEDLPFQQGDRILVTAHVDDEWWSG--RINGREGFFPKAFV 954

  Fly  2566 E 2566
            |
Zfish   955 E 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAP	NP_001369075.1	MDN1	<43..328	CDD:227596
		Sorb	1959..2003	CDD:413404	9/48 (19%)
		SH3_Sorbs_1	2315..2367	CDD:212715	16/51 (31%)
		SH3_Sorbs_2	2384..2436	CDD:212716	15/56 (27%)
		SH3_Sorbs_3	2514..2567	CDD:212714	17/53 (32%)
sh3d19	XP_009289295.1	SH3	647..696	CDD:302595	12/60 (20%)
		SH3	732..782	CDD:302595	16/49 (33%)
		SH3_Eve1_3	809..859	CDD:212750	13/49 (27%)
		SH3_Eve1_4	904..953	CDD:212751	16/51 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR14167
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010