DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAP and POSH

DIOPT Version :9

Sequence 1:	NP_001369075.1	Gene:	CAP / 36084	FlyBaseID:	FBgn0033504	Length:	2568	Species:	Drosophila melanogaster
Sequence 2:	NP_523776.1	Gene:	POSH / 36990	FlyBaseID:	FBgn0040294	Length:	838	Species:	Drosophila melanogaster

Alignment Length:	348	Identity:	95/348 - (27%)
Similarity:	134/348 - (38%)	Gaps:	110/348 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  2316 ARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRP 2380
            |.|||:|....:.:|.|:|||.|.|:.:||.||:.|:.|...|..|.:||::      ..|...|
  Fly   140 AYALFDFASGEATDLKFKKGDLILIKHRIDNNWFVGQANGQEGTFPINYVKV------SVPLPMP 198

  Fly  2381 SEGQARAKYNFQAQSGIE---LSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEV------ 2436
               |..|.|:|:.....|   |...|..::.:.||||.||.||:|....||||.::||:
  Fly   199 ---QCIAMYDFKMGPNDEEGCLEFKKSTVIQVMRRVDHNWAEGRIGQTIGIFPIAFVELNAAAKK 260

  Fly  2437 LTDIGAE-----------------DIAARTTTVIT------------------SQSTTNLRPNLD 2466
            |.|.|..                 .:.....||:|                  :.|:.|..||..
  Fly   261 LLDSGLHTHPFCHPPKQQGQRALPPVPVIDPTVVTESSSGSSNSTPGSSNSSSTSSSNNCSPNHQ 325

  Fly  2467 VLRTNI----------------------NNEFNTLTQNGAQPPNGILKETR-------TLHKTDA 2502
            :...|.                      .:..|.|...||  |..:|:..|       ..|:...
  Fly   326 ISLPNTPQHVVASGSASVRFRDKGAKEKRHSLNALLGGGA--PLSLLQTNRHSAEILSLPHELSR 388

  Fly  2503 LHVDTSSE-------------------------PLAYRALYKYRPQNSDELELLEGDVVHVLEKC 2542
            |.|.:|:.                         |..|.||:.|:|:.:|||||.:|.|..|.|:|
  Fly   389 LEVSSSTALKPTSAPQTSRVLKTTVQQQMQPNLPWGYLALFPYKPRQTDELELKKGCVYIVTERC 453

  Fly  2543 DDGWFVGTSQRTGCFGTFPGNYV 2565
            .||||.|.:. ....|.|||||:
  Fly   454 VDGWFKGKNW-LDITGVFPGNYL 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAP	NP_001369075.1	MDN1	<43..328	CDD:227596
		Sorb	1959..2003	CDD:413404
		SH3_Sorbs_1	2315..2367	CDD:212715	22/50 (44%)
		SH3_Sorbs_2	2384..2436	CDD:212716	21/54 (39%)
		SH3_Sorbs_3	2514..2567	CDD:212714	26/52 (50%)
POSH	NP_523776.1	RING	11..53	CDD:238093
		SH3	139..191	CDD:302595	22/50 (44%)
		SH3_SH3RF_2	199..251	CDD:212721	20/51 (39%)
		SH3_SH3RF_3	424..477	CDD:212717	26/53 (49%)
		SH3_SH3RF_C	782..836	CDD:212719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	41	1.000	Domainoid score	I3230
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46655
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR14167
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	4.010