DRSC/TRiP Functional Genomics Resources

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Protein Alignment CAP and Sh3rf1

DIOPT Version :9

Sequence 1:NP_001369075.1 Gene:CAP / 36084 FlyBaseID:FBgn0033504 Length:2568 Species:Drosophila melanogaster
Sequence 2:NP_942059.1 Gene:Sh3rf1 / 306417 RGDID:735154 Length:894 Species:Rattus norvegicus


Alignment Length:379 Identity:103/379 - (27%)
Similarity:145/379 - (38%) Gaps:137/379 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly  2316 ARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRP 2380
            |:||:|::|:...:|.|.|||.|.:|||:|.|||.||.|.:.|..|.::|:|:.      |..:|
  Rat   139 AKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGVHGFFPTNFVQIIK------PLPQP 197

  Fly  2381 SEGQARAKYNFQAQSGIE----LSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVE------ 2435
            .. |.:|.|:|:.:....    |...|.:::|:.||||.||.||.:|::.||||.||||      
  Rat   198 PP-QCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAK 261

  Fly  2436 ----------------------------------------------------------------- 2435
                                                                             
  Rat   262 QLIEWDKPPVPGVDTAECPSATAAQSSSASKHSDTKKNTRKRHSFTSLTMANKSSQASQNRHSME 326

  Fly  2436 ----VLTDIGAEDIAARTTTV------ITSQ---STTNL----RPNLDV-------LRTNINNEF 2476
                ||........|||.:.:      ..||   |||.|    .|:..|       ..|::..:.
  Rat   327 ISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTPPPSSPVTTGPSFTFPTDVPYQA 391

  Fly  2477 NTLTQNGAQPPNGILKETRTLHKTDA------------------------------LHVDTSSEP 2511
            ...|.|...||..:| .|..|..|.:                              .|:...:.|
  Rat   392 ALGTMNPPLPPPPLL-ATTVLASTPSGATAAAVAAAAAAVAAGVGPRPAVGSTEQIAHLRPQTRP 455

  Fly  2512 LAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYV 2565
            ..|.|:|.|.|:..|||||.:|::..|.|:|.|||:.|||..|...|.||||||
  Rat   456 SVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWYKGTSMHTSKIGVFPGNYV 509

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CAPNP_001369075.1 MDN1 <43..328 CDD:227596
Sorb 1959..2003 CDD:413404
SH3_Sorbs_1 2315..2367 CDD:212715 24/50 (48%)
SH3_Sorbs_2 2384..2436 CDD:212716 24/130 (18%)
SH3_Sorbs_3 2514..2567 CDD:212714 28/52 (54%)
Sh3rf1NP_942059.1 RING 11..56 CDD:238093
SH3 137..190 CDD:302595 24/50 (48%)
SH3_SH3RF1_2 200..254 CDD:212863 21/53 (40%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 274..323 0/48 (0%)
Interaction with RAC1. /evidence=ECO:0000250|UniProtKB:Q7Z6J0 293..363 8/69 (12%)
Interaction with AKT2. /evidence=ECO:0000250 448..551 30/62 (48%)
SH3 457..511 CDD:302595 28/53 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 526..556
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 682..751
SH3_SH3RF_C 839..893 CDD:212719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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