DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CAP and Sh3rf3

DIOPT Version :9

Sequence 1:	NP_001369075.1	Gene:	CAP / 36084	FlyBaseID:	FBgn0033504	Length:	2568	Species:	Drosophila melanogaster
Sequence 2:	XP_017457292.1	Gene:	Sh3rf3 / 294557	RGDID:	1589772	Length:	878	Species:	Rattus norvegicus

Alignment Length:	374	Identity:	113/374 - (30%)
Similarity:	156/374 - (41%)	Gaps:	119/374 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  2285 TPSQKSPIALNRYDDFPTDVTLKSLVGPKTVARALFNFQGQTSKELSFRKGDTIYIRRQIDANWY 2349
            |.|.....|.||  ..|....|..|    ..|:||::::|:...:|.|.|||.|.:||::|.|||
  Rat   168 TSSSLCDAATNR--SVPVAKNLSQL----PYAKALYSYEGKEPGDLKFNKGDIIILRRKVDENWY 226

  Fly  2350 EGEHNAMIGLLPASYVEIVSRDGARTPSKRPSEGQARAKYNFQAQSGIE----LSLNKGELVTLT 2410
            .||.....|.|||||::.:    ...|...|   |.:|.|:|:.:...:    |:..|.|::|:.
  Rat   227 HGELQGTHGFLPASYIQCM----RPLPQTLP---QGKALYDFEMKDRDQDKDCLTFTKDEVLTVI 284

  Fly  2411 RRVDGNWFEGKIANRKGIFPCSYVEVLTD-----IGAEDIAARTTT------VITSQSTT--NLR 2462
            ||||.||.||.:.::.||||..||| |.|     |..:.:....||      :::|..:|  |:.
  Rat   285 RRVDDNWAEGMLGDKIGIFPLLYVE-LNDSAKQLIEMDKLCPAATTAYNYDALLSSDPSTVANVA 348

  Fly  2463 PNLDVLRTNINNEFNTLTQNGA----QPPNGILKETRTLHKTDALHVD----------------- 2506
            |.            .||:.:||    |......|..:..|...||.|.
  Rat   349 PG------------PTLSSSGAVSAFQRRVDSKKNAKKRHSFTALSVTHKSSQASSHRHSMEISA 401

  Fly  2507 ----TSSEPLA---------------------------------------------------YRA 2516
                :||:|.|                                                   |.|
  Rat   402 PVLISSSDPRAAARIGELAHLSCAVPTQDSSSAGPVPTAIPRAAAVAGEQGMSPKVQLPLNMYLA 466

  Fly  2517 LYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYV 2565
            ||.|:||.:|||||.:|::..|||||.||||.|.|.:||..|.||||||
  Rat   467 LYAYKPQKNDELELRKGEMYRVLEKCQDGWFKGASLKTGISGVFPGNYV 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CAP	NP_001369075.1	MDN1	<43..328	CDD:227596
		Sorb	1959..2003	CDD:413404
		SH3_Sorbs_1	2315..2367	CDD:212715	24/51 (47%)
		SH3_Sorbs_2	2384..2436	CDD:212716	22/55 (40%)
		SH3_Sorbs_3	2514..2567	CDD:212714	33/52 (63%)
Sh3rf3	XP_017457292.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910