DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12910 and si:zfos-464b6.2

DIOPT Version :9

Sequence 1:	NP_001260858.1	Gene:	CG12910 / 36082	FlyBaseID:	FBgn0033502	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_003200543.3	Gene:	si:zfos-464b6.2 / 794433	ZFINID:	ZDB-GENE-030131-5337	Length:	474	Species:	Danio rerio

Alignment Length:	462	Identity:	109/462 - (23%)
Similarity:	180/462 - (38%)	Gaps:	85/462 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VYFALSALVASAMLVLVY---ISMRSSLN--ERLREDLAKAQRQMIFERPNPHWDYSNSWRRIGN 71
            :::.:..:.|...:..:|   .:..:|..  |....|.....|..:.|.|.......|....|..
Zfish    34 IFYVIGFVSAFTFIAFIYFQDFAQNASWQTYEPKPTDAPPTNRTFLEEAPTACGVIINEGPMIKV 98

  Fly    72 STLRHEIYSAYFDARTDIVGNVRMDDEQMTIGSLRIFAILPERLRDSSINCIVRFSDFSSQEIKA 136
            ..|...:..:|.|.|...|.::.:.:.|..:                :.:|::   ..:.:.:..
Zfish    99 GDLNTYVTGSYMDHRFREVKSIAIVNRQQLV----------------TYSCVL---CCNGKNVTT 144

  Fly   137 EEAGAMHDVH-NNTFAAWSIMCPLHASRRSPLRLPQAVALAYASNRLSHLSPTFIQISYPRNMTN 200
            ....|:|..| ...:...:|.|||:.....|..    |||..::|...  |.|..|....|::..
Zfish   145 LAHYAIHSDHFGFEYGTATIACPLNDECLKPTH----VALTSSANHSE--SITSFQSIMNRDVPA 203

  Fly   201 MFGRSRPTISVCVGPLHENYSNVLRLVEFVEMYRLQGATHFYFYYVEASEEVLRVLEHYQRIGLA 265
            .|...   .:||:..::: |:|||.|||.:||:||.|||....|.......|.:||::|...|..
Zfish   204 AFPHQ---FTVCISVMYD-YTNVLNLVEAMEMFRLLGATRVAIYRTNCDSNVQKVLDYYVERGFV 264

  Fly   266 DVFEWNVQAHMQ------------DVHYAGIVAQFNDCVYRANVVDNFRYAAVVDLDEVVMPLKH 318
            :|..|.::.|:|            ::||.|.:...||||||  .:...||.|:.|:||:::|...
Zfish   265 EVIPWTIKKHVQVSRGWRKDVSGGELHYYGQIPALNDCVYR--YMYQSRYVALHDMDELILPFGV 327

  Fly   319 NTLADYLRQCDE--GRTAGFVFRNVFF-------HRRDSNDTFNAPSHVLNRLLYTQSKVRRTLE 374
            .|..:.|...::  |.|.||.|.|..|       .|.|.||..:...  .|.|.|    ::|...
Zfish   328 KTWTEMLPNLEKMYGTTFGFEFENNQFPFTSKANRRYDVNDWESVRG--TNILKY----IQRVPN 386

  Fly   375 VLPAYIRSKVVVNARAI-----------VEMGNHQVYRAAPGYADHVVHPTVGLLFHYRDKCINC 428
            ...|:...||:||.|.:           |.:|.|.|.          |:..|..::|.::.....
Zfish   387 DPNAFNNFKVIVNPRLVLMATVHGLLDTVNVGKHTVR----------VNRNVARMYHSKNLTYPL 441

  Fly   429 KMVLIVD 435
            ...||.|
Zfish   442 NTNLIPD 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12910	NP_001260858.1	Glyco_transf_92	209..423	CDD:279961	72/245 (29%)
si:zfos-464b6.2	XP_003200543.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7575
eggNOG	1	0.900	-	-		E1_KOG4735
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I5046
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561250at33208
OrthoFinder	1	1.000	-	-		FOG0003939
OrthoInspector	1	1.000	-	-		mtm6493
orthoMCL	1	0.900	-	-		OOG6_109876
Panther	1	1.100	-	-	O	PTHR21461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.870