DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syb and vamp8

DIOPT Version :9

Sequence 1:	NP_001137633.1	Gene:	Syb / 36080	FlyBaseID:	FBgn0003660	Length:	152	Species:	Drosophila melanogaster
Sequence 2:	NP_956053.1	Gene:	vamp8 / 327007	ZFINID:	ZDB-GENE-030131-5215	Length:	124	Species:	Danio rerio

Alignment Length:	131	Identity:	40/131 - (30%)
Similarity:	73/131 - (55%)	Gaps:	15/131 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PNANDNYNQFGDHQIRNNNAAQKKLQQTQAKVDEVVGIMRVNVEKVLERDQKLSELGERADQLEQ 88
            ||:.       :|:...::....:::..|::||.|..||..||:::|.|.::|.:|..:::.||.
Zfish     6 PNST-------EHREGESSQDADRVKALQSQVDGVKDIMTQNVDRILARGERLDDLMGKSEDLEA 63

  Fly    89 GASQFEQQAGKLKRKQWWANMKMMIILGVIAVVLLIIVL---VSVWPSSSDSGSGGGNKAITQAP 150
            ||..|:|.:.|:.|..||.|:|:::::.||.:|:|:|::   ..|.|.     ||...|..|..|
Zfish    64 GAQNFKQTSQKVARAFWWKNVKLIVLIVVIVLVILLIIIFLATGVIPV-----SGSAPKPPTVTP 123

  Fly   151 P 151
            |
Zfish   124 P 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syb	NP_001137633.1	Synaptobrevin	44..130	CDD:395764	29/88 (33%)
vamp8	NP_956053.1	Synaptobrevin	19..>85	CDD:279324	23/65 (35%)
vamp8	NP_956053.1	R-SNARE_VAMP8	21..85	CDD:277221	23/63 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000385
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45701
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1430
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940