Protein Alignment Hdc and gadA

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_417974.1
• Gene: gadA / 948027
• ECOCYCID: EG50009
• Length: 466
• Species: Escherichia coli
• Alignment Length: 449
• Identity: 104/449 - (23%)
• Similarity: 166/449 - (36%)
• Gaps: 127/449 - (28%)

  Fly   104 TWASSPACTELEI-IVMNWLGK------------MIGLPDAFLHLSSQSQGGGVLQTT--ASEAT 153
            ||........::: |..||:.|            .:.:.....|..:...|..|...|  :|||
E. coli    66 TWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEA- 129

  Fly   154 LVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSSVEKAALI-GLVRM------RYIE 211
              |:|.|.... .|:.:|                 .:.|....:|..|: |.|::      ||.:
E. coli   130 --CMLGGMAMK-WRWRKR-----------------MEAAGKPTDKPNLVCGPVQICWHKFARYWD 174

  Fly   212 AD-DDLAMR-GKLL---REAIE--DDIKQGLVPFWVCATLGT--TGSCSF-----DNLE----EI 258
            .: .::.|| |:|.   :..||  |:...|:||     |.|.  ||:..|     |.|:    :.
E. coli   175 VELREIPMRPGQLFMDPKRMIEACDENTIGVVP-----TFGVTYTGNYEFPQPLHDALDKFQADT 234

  Fly   259 GIVCAEHHLWLHVDAAYAG--SAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATAL---WV- 317
            ||     .:.:|:|||..|  :.|:.|:. .|...:.|..||:.:..|     |....|   ||
E. coli   235 GI-----DIDMHIDAASGGFLAPFVAPDI-VWDFRLPRVKSISASGHK-----FGLAPLGCGWVI 288

  Fly   318 -RDSTAVHR--TFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIRE 379
             ||..|:.:  .|||:  ||..:....|::|..   |..:        .:.:.|....|.|....
E. coli   289 WRDEEALPQELVFNVD--YLGGQIGTFAINFSR---PAGQ--------VIAQYYEFLRLGREGYT 340

  Fly   380 GVRLAQKFEALVLAD-------HRFELPAKRHLGL--VVFRIRGDNEITEKLLKRLNHRGNLHCI 435
            .|:.|....|..|||       :.|....:...|:  |.|::: |.|.....|..|:.|
E. coli   341 KVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLK-DGEDPGYTLYDLSER------ 398

  Fly   436 PSSLKGQYVIRFTITSTHTTLDDIVKDWMEIRQ-----VASTVLEEMNITISNRVYLKE 489
             ..|:|..|..||:....|   |||...:..|:     .|..:||:...::.   ||.:
E. coli   399 -LRLRGWQVPAFTLGGEAT---DIVVMRIMCRRGFEMDFAELLLEDYKASLK---YLSD 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	84/366 (23%)
gadA	NP_417974.1	Glu-decarb-GAD	16..449	CDD:130848	103/446 (23%)