Protein Alignment Hdc and DPL1

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_010580.1
• Gene: DPL1 / 851888
• SGDID: S000002702
• Length: 589
• Species: Saccharomyces cerevisiae
• Alignment Length: 524
• Identity: 101/524 - (19%)
• Similarity: 190/524 - (36%)
• Gaps: 140/524 - (26%)

  Fly    38 MRQLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLG 102
            :..|:|.:...||:....::...:.::     |.|:.....|..|....|.:.
Yeast   155 LNDLIPHTQWKEGKVSGAVYHGGDDLI-----HLQTIAYEKYCVANQLHPDVF------------ 202

  Fly   103 FTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQR 167
                  ||..::|..|::.:.:|...|        ...|.|...:..:|:.|:..|:.:..|:
Yeast   203 ------PAVRKMESEVVSMVLRMFNAP--------SDTGCGTTTSGGTESLLLACLSAKMYAL-- 251

  Fly   168 FHERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADD-----DLAMRGKLLREAI 227
               .|.|..:.||.|.:.      ||:..:|||....:::|::|.|.     ||....|.:.:
Yeast   252 ---HHRGITEPEIIAPVT------AHAGFDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINK-- 305

  Fly   228 EDDIKQGLVPFWVCATLGTTGSC-SF-----DNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEFR 286
                          .|:...||. :|     |::|.:|.:..::.|.||||:. .||..:....:
Yeast   306 --------------NTILLVGSAPNFPHGIADDIEGLGKIAQKYKLPLHVDSC-LGSFIVSFMEK 355

  Fly   287 TWLRGIERAD-------SIAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEP-----LY----LQ 335
            ...:.:...|       ||:.:..|:......::.:..|:|......:.|.|     ||    |.
Yeast   356 AGYKNLPLLDFRVPGVTSISCDTHKYGFAPKGSSVIMYRNSDLRMHQYYVNPAWTGGLYGSPTLA 420

  Fly   336 HENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELP 400
            ....|..|               :..|..:.:.|..|.....:|.|..|.||:..:    :..:|
Yeast   421 GSRPGAIV---------------VGCWATMVNMGENGYIESCQEIVGAAMKFKKYI----QENIP 466

  Fly   401 AKRHLG-----LVVFRIRGDN--EITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDD 458
            ....:|     ::.|..:..|  |::::|.|:..|...|. .|.:|.    :.||..|.|
Yeast   467 DLNIMGNPRYSVISFSSKTLNIHELSDRLSKKGWHFNALQ-KPVALH----MAFTRLSAH----- 521

  Fly   459 IVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLL------LSNSPLSPKVVNGSF 517
             |.|  ||..:..|.::|:.         .|:..|....|:|.|      :..:.::.|::.|..
Yeast   522 -VVD--EICDILRTTVQELK---------SESNSKPSPDGTSALYGVAGSVKTAGVADKLIVGFL 574

  Fly   518 AAIF 521
            .|::
Yeast   575 DALY 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	75/406 (18%)
DPL1	NP_010580.1	GadA	106..543	CDD:223154	94/487 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810