Protein Alignment Hdc and GAD2

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001117556.1
• Gene: GAD2 / 842908
• AraportID: AT1G65960
• Length: 494
• Species: Arabidopsis thaliana
• Alignment Length: 521
• Identity: 104/521 - (19%)
• Similarity: 186/521 - (35%)
• Gaps: 138/521 - (26%)

  Fly    40 QLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFT 104
            |::.:...::|.|...:.|.|        |.|..|.              ...::.|:||.....
plant    43 QIIKDELMLDGNPRLNLASFV--------TTWMEPE--------------CDKLIMDSINKNYVD 85

  Fly   105 WASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTR-AIQRF 168
            ....|..|||:...:|.:.::...|     |.......||....:|||.::..||.:.: ..:|.
plant    86 MDEYPVTTELQNRCVNIIARLFNAP-----LEESETAVGVGTVGSSEAIMLAGLAFKRKWQNKRK 145

  Fly   169 HERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMR-------YIEADDDLAMRGKLLREA 226
            .|..|..:...:....|..|       .||.|....|.::       |...|.|.|      .|.
plant   146 AEGKPYDKPNIVTGANVQVC-------WEKFARYFEVELKEVNLSEGYYVMDPDKA------AEM 197

  Fly   227 IEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGIVCA---EHHLW---LHVDAAYAG--SAFICP 283
            ::::      ...|.|.||:|.:..|::::.:..:..   |...|   :|||||..|  :.||.|
plant   198 VDEN------TICVAAILGSTLNGEFEDVKRLNDLLVKKNEETGWNTPIHVDAASGGFIAPFIYP 256

  Fly   284 EFRTWLRGIERADSIAFNPSKWLMVHFDATALWV----RDSTAVHRTFNVEPLYLQHENSGVAVD 344
            |.. |...:....||..:..|:.:|:  |...||    .:.......|::.  ||..:.....::
plant   257 ELE-WDFRLPLVKSINVSGHKYGLVY--AGIGWVVWRAAEDLPEELIFHIN--YLGADQPTFTLN 316

  Fly   345 FMHW--QIPLSRRFRALKVWFVLRSYGIKGLQRH-------IREGVRLAQKFE-----------A 389
            |...  || :::.::.:::.|    .|.|.:..:       ::||:...::|.           |
plant   317 FSKGSSQI-IAQYYQLIRLGF----EGYKNVMENCIENMVVLKEGIEKTERFNIVSKDQGVPVVA 376

  Fly   390 LVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHT 454
            ..|.||.|               ..:.||:| :|:|.......:.:|:..:...|:|..|....:
plant   377 FSLKDHSF---------------HNEFEISE-MLRRFGWIVPAYTMPADAQHITVLRVVIREDFS 425

  Fly   455 -------------------TLDDIVKDWMEIRQVASTVLEE-------MNITISNRVYLKETKEK 493
                               ||...:...|.|..:|..|.|:       |.:.:..|.::||.|:.
plant   426 RTLAERLVADISKVLHELDTLPSKISKKMGIEGIAENVKEKKMEKEILMEVIVGWRKFVKERKKM 490

  Fly   494 N 494
            |
plant   491 N 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	82/412 (20%)
GAD2	NP_001117556.1	Glu-decarb-GAD	17..444	CDD:130848	91/472 (19%)