Protein Alignment Hdc and GAD

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_197235.1
• Gene: GAD / 831599
• AraportID: AT5G17330
• Length: 502
• Species: Arabidopsis thaliana
• Alignment Length: 494
• Identity: 96/494 - (19%)
• Similarity: 192/494 - (38%)
• Gaps: 94/494 - (19%)

  Fly    40 QLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFT 104
            |::.:...::|.|...:.|.|        |.|..|.              ...::..:||.....
plant    44 QIINDELMLDGNPRLNLASFV--------TTWMEPE--------------CDKLIMSSINKNYVD 86

  Fly   105 WASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTR-AIQRF 168
            ....|..|||:...:|.:..:...|     |.......||....:|||.::..||.:.: ..:|.
plant    87 MDEYPVTTELQNRCVNMIAHLFNAP-----LEEAETAVGVGTVGSSEAIMLAGLAFKRKWQNKRK 146

  Fly   169 HERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQ 233
            .|..|..:...:....|..|       .||.|....|.::.::..:...:...  ::|: |.:.:
plant   147 AEGKPVDKPNIVTGANVQVC-------WEKFARYFEVELKEVKLSEGYYVMDP--QQAV-DMVDE 201

  Fly   234 GLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHL---W---LHVDAAYAG--SAFICPEFRTWLR 290
            ..:  .|.|.||:|.:..|::::.:..:..|.:.   |   :|||||..|  :.|:.||.. |..
plant   202 NTI--CVAAILGSTLNGEFEDVKLLNDLLVEKNKETGWDTPIHVDAASGGFIAPFLYPELE-WDF 263

  Fly   291 GIERADSIAFNPSKWLMVHFDATALWV----RDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQIP 351
            .:....||..:..|:.:|:  |...||    ::.......|::.  ||..:.....::|......
plant   264 RLPLVKSINVSGHKYGLVY--AGIGWVIWRNKEDLPEELIFHIN--YLGADQPTFTLNFSKGSSQ 324

  Fly   352 LSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLAD-----HRFELPAK-RHLGLVVF 410
            :..::..|   ..|...|.:.:..:.||.:        :||.:     .||.:.:| ..:.||.|
plant   325 VIAQYYQL---IRLGHEGYRNVMENCRENM--------IVLREGLEKTERFNIVSKDEGVPLVAF 378

  Fly   411 RIRGDNEITE----KLLKRLNHRGNLHCIPSSLKGQYVIR------FTITSTHTTLDDIVKDWME 465
            .::..:..||    .:|:|.......:.:|.:.:...|:|      |:.|.....:.||.|...|
plant   379 SLKDSSCHTEFEISDMLRRYGWIVPAYTMPPNAQHITVLRVVIREDFSRTLAERLVIDIEKVMRE 443

  Fly   466 IRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLS 504
            :.::.|.|:.::::          .:||:|:...:|:::
plant   444 LDELPSRVIHKISL----------GQEKSESNSDNLMVT 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	77/391 (20%)
GAD	NP_197235.1	Glu-decarb-GAD	16..445	CDD:130848	90/455 (20%)