Protein Alignment Hdc and GAD4

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001324150.1
• Gene: GAD4 / 814732
• AraportID: AT2G02010
• Length: 545
• Species: Arabidopsis thaliana
• Alignment Length: 563
• Identity: 117/563 - (20%)
• Similarity: 211/563 - (37%)
• Gaps: 131/563 - (23%)

  Fly     3 FKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLP------ESAPIEGEPWPKIFSDVE 61
            ||...|..|...|.:.....:..:..:....:..|:|..||      .|.|.|..  .:|.:|
plant    40 FKPKNQSSKLKEDMVLSKTVSESDVSIHSTFASRYVRNSLPRFEMPENSIPKEAA--YQIIND-- 100

  Fly    62 RIVMPG---------ITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEII 117
            .:::.|         :|.|..|.              ...::.::||.........|..|||:..
plant   101 ELMLDGNPRLNLASFVTTWMEPE--------------CDKLMMESINKNYVDMDEYPVTTELQNR 151

  Fly   118 VMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEI-N 181
            .:|.:.::...|     |.......||....:|||.::..||.:.:...:...:...|....| .
plant   152 CVNMIARLFNAP-----LGDGEAAVGVGTVGSSEAIMLAGLAFKRQWQNKRKAQGLPYDKPNIVT 211

  Fly   182 ARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDDLAMRGKLLRE--AIEDDIKQGLV----PFWV 240
            ...|..|       .||.|       ||.|.:    ::...|||  .:.|.:|...:    ...|
plant   212 GANVQVC-------WEKFA-------RYFEVE----LKEVNLREDYYVMDPVKAVEMVDENTICV 258

  Fly   241 CATLGTTGSCSFDNLEEIGIVCAEHHL---W---LHVDAAYAG--SAFICPEFRTWLRGIERADS 297
            .|.||:|.:..|::::.:..:..|.:.   |   :|||||..|  :.|:.||.. |...:....|
plant   259 AAILGSTLTGEFEDVKLLNDLLVEKNKQTGWDTPIHVDAASGGFIAPFLYPELE-WDFRLPLVKS 322

  Fly   298 IAFNPSKWLMVHFDATALWVRDSTAVHRT---------FNVEPLYLQHENSGVAVDFMHW--QIP 351
            |..:..|:.:|:  |...||     |.||         |::.  ||..:.....::|...  |:
plant   323 INVSGHKYGLVY--AGIGWV-----VWRTKTDLPDELIFHIN--YLGADQPTFTLNFSKGSSQV- 377

  Fly   352 LSRRFRALKVWFVLRSYGIKGLQRHIREGVR-LAQKFEALVLADHRFELPAKRH-LGLVVFRIRG 414
            :::.::.:::.|    .|.:.:..:.||.:. |.|..|    ...||::.:|.: :.||.|.::.
plant   378 IAQYYQLIRLGF----EGYRNVMDNCRENMMVLRQGLE----KTGRFKIVSKENGVPLVAFSLKD 434

  Fly   415 DNEITE----KLLKRLNHRGNLHCIPSSLKGQYVIRFTITS--THTTLDDIVKDWMEIRQVASTV 473
            .:...|    ..|:|.......:.:|:..:...|:|..|..  :.|..:.:|.|:       ..|
plant   435 SSRHNEFEVAHTLRRFGWIVPAYTMPADAQHVTVLRVVIREDFSRTLAERLVADF-------EKV 492

  Fly   474 LEEMNITISNRVYLK--------------ETKEKNEAFGSSLL 502
            |.|:: |:..||:.|              ||:.:..|:...||
plant   493 LHELD-TLPARVHAKMANGKVNGVKKTPEETQREVTAYWKKLL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	90/420 (21%)
GAD4	NP_001324150.1	Glu-decarb-GAD	68..497	CDD:130848	103/495 (21%)