Protein Alignment Hdc and GAD3

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_178309.1
• Gene: GAD3 / 814731
• AraportID: AT2G02000
• Length: 500
• Species: Arabidopsis thaliana
• Alignment Length: 517
• Identity: 106/517 - (20%)
• Similarity: 201/517 - (38%)
• Gaps: 114/517 - (22%)

  Fly    16 YIADYLENIRERRVFPDVS----PGYMRQLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHM 76
            :.:.|:.|...|...|..|    ..|  |::.:....:|.|...:.|.|        |.|..|.
plant    18 FASRYVRNSISRFEIPKNSIPKEAAY--QIINDELKFDGNPRLNLASFV--------TTWMEPE- 71

  Fly    77 HAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQG 141
                         ...::.::||.........|..|:|:...:|.:.::...|     |......
plant    72 -------------CDKLMMESINKNNVEMDQYPVTTDLQNRCVNMIARLFNAP-----LGDGEAA 118

  Fly   142 GGVLQTTASEATLVCLLA------GRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSSVEKAA 200
            .||....:|||.::..||      .:.:|:...::|......|.|...|..:.   .:..||
plant   119 IGVGTVGSSEAVMLAGLAFKRQWQNKRKALGLPYDRPNIVTGANIQVCLEKFA---RYFEVE--- 177

  Fly   201 LIGLVRMR--YIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGIVCA 263
             :..|::|  |...|.|.|:      |.::::      ...|.|.||:|.:..|::::.:..:..
plant   178 -LKEVKLREGYYVMDPDKAV------EMVDEN------TICVVAILGSTLTGEFEDVKLLNDLLV 229

  Fly   264 EHHL---W---LHVDAAYAG--SAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDS 320
            |.:.   |   :|||||..|  :.|:.|:.. |...:....||..:..|:.:|:  |...||
plant   230 EKNKKTGWDTPIHVDAASGGFIAPFLYPDLE-WDFRLPLVKSINVSGHKYGLVY--AGIGWV--- 288

  Fly   321 TAVHRT---------FNVEPLYLQHENSGVAVDFMHW--QIPLSRRFRALKVWFVLRSYGIKGLQ 374
              |.||         |::.  ||..:.....::|...  |: :::.::.:::.|    .|.:.:.
plant   289 --VWRTKTDLPDELIFHIN--YLGADQPTFTLNFSKGSSQV-IAQYYQLIRLGF----EGYRNVM 344

  Fly   375 RHIREGVR-LAQKFEALVLADHRFELPAKRH-LGLVVFRIRGDNEITE----KLLKRLNHRGNLH 433
            .:.||.:. |.|..|    ...||.:.:|.: :.||.|.::..:...|    ::|:|.......:
plant   345 DNCRENMMVLRQGLE----KTGRFNIVSKENGVPLVAFSLKDSSRHNEFEVAEMLRRFGWIVPAY 405

  Fly   434 CIPSSLKGQYVIRFTITS--THTTLDDIVKDWMEIRQVASTVLEEMNITISNRVYLKETKEK 493
            .:|:..:...|:|..|..  :.|..:.:|.|:       ..||.|:: |:..||:.|....|
plant   406 TMPADAQHVTVLRVVIREDFSRTLAERLVADF-------EKVLHELD-TLPARVHAKMASGK 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	83/406 (20%)
GAD3	NP_178309.1	Glu-decarb-GAD	16..445	CDD:130848	101/500 (20%)