Protein Alignment Hdc and hdc

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001429008.1
• Gene: hdc / 793609
• ZFINID: ZDB-GENE-080102-5
• Length: 608
• Species: Danio rerio
• Alignment Length: 630
• Identity: 316/630 - (50%)
• Similarity: 403/630 - (63%)
• Gaps: 67/630 - (10%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            |..:||..||||||:||..||..||||||.|||.||:||.|||.|||.|.|.|..|..|||.|:|
Zfish     1 MQPQEYMLRGKEMVEYIHQYLTGIRERRVVPDVQPGFMRPLLPSSAPYEPEDWSTIMQDVENIIM 65

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:.||||||||||||||||.|||||||||||||||||||||||||||||:.|::||.|.:||||
Zfish    66 PGVVHWQSPHMHAYFPALNSWPSLLGDMLADAINCLGFTWASSPACTELEMCVLDWLCKALGLPD 130

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGR-TRAIQRFHE-RHPGYQDAEINARLVAYCSDQAH 193
            .:||...||.|||:||:|.||.|||.|||.| .|.:|...| .|....::.:|:|||||.|||||
Zfish   131 HYLHHHPQSTGGGILQSTVSECTLVALLAARKDRILQMKSEATHTDTDESVLNSRLVAYASDQAH 195

  Fly   194 SSVEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEI 258
            ||||||.||.||::|:::.|...::||:.|:.|:|:|.:.||:|..||||||:||.||||.|:|:
Zfish   196 SSVEKAGLISLVKIRFLQTDAVFSLRGETLQRAVEEDRRSGLIPVMVCATLGSTGVCSFDRLDEL 260

  Fly   259 GIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAV 323
            |.||....|||||||||||||.:|||.|.:|.||:.|||..||||||::||||.||.||::...:
Zfish   261 GPVCVREGLWLHVDAAYAGSALLCPELRYFLDGIQFADSFVFNPSKWMLVHFDCTAFWVKNKMKL 325

  Fly   324 HRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388
            .:||.|:||||:|:||. |.||||||||||||||:||:|||:||:|:|.||.|||.||.:|:.||
Zfish   326 QQTFTVDPLYLRHDNSN-ATDFMHWQIPLSRRFRSLKLWFVIRSFGLKKLQEHIRHGVEMAKLFE 389

  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453
            :||..|..|::||:||||||||.:|..|..|::||::|...|.:..||:::..|.::||::||..
Zfish   390 SLVRNDTHFQIPAQRHLGLVVFCLRAGNAATQELLRKLTRSGRMFLIPAAVGNQLILRFSVTSQL 454

  Fly   454 TTLDDIVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFA 518
            ||..||.:||..|:|.|..||:...:|....|    |.:. |:...||.:...|:..:
Zfish   455 TTEQDIRRDWSLIQQAAREVLQSGVVTRQPSV----TSDP-ESEPESLTIHTEPMLDQ------- 507

  Fly   519 AIFDADEFLAKTYAGVRIAHQESPSMRRRVRGILMSGKQFSLDSHMDVVVQTTLDAGNGATRTST 583
                            |:..|   ..||.||....|.:               |....|.|:|
Zfish   508 ----------------RLVRQ---GQRRAVRSYSCSAE---------------LPPAPGRTQT-- 536

  Fly   584 TNSYGHTTSAAQANSERQASIQEDNEESPEETELLSLCRTSNVPS 628
                           .|.|.:|...|: ||..:...|.:.::|||
Zfish   537 ---------------HRDAPLQLIPEQ-PERPQHRRLLKFNSVPS 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	241/379 (64%)
hdc	NP_001429008.1	None