Protein Alignment Hdc and ddc

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001011289.1
• Gene: ddc / 496742
• XenbaseID: XB-GENE-983285
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 252/476 - (52%)
• Similarity: 347/476 - (72%)
• Gaps: 3/476 - (0%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            |:..|:|:|||:||||:|||||.|..|:|||||.|||:|.|:|:|||.|||.:.:|..||||::|
 Frog     1 MNASEFRKRGKDMVDYVADYLEQIESRQVFPDVEPGYLRPLIPDSAPEEGETYEEIIKDVERVIM 65

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:|||.||:..||||..:|.|:||.|||..||.|:||:|||||||||||.::::|||||||||:
 Frog    66 PGVTHWHSPYFFAYFPTGSSYPALLADMLCGAIGCIGFSWASSPACTELETVMLDWLGKMIGLPE 130

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            .|| ..::.:||||:|.|||||||:.|||.||:..:|....:|...:|||.:|:|||.|||||||
 Frog   131 QFL-AGNKGEGGGVIQGTASEATLMALLAARTKVTRRLQAENPKLTEAEIVSRMVAYSSDQAHSS 194

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            ||:|.||..|||:.|.:|::...||:.|::|:|:|..:||:|.:.|||||||.||:||||.|:|.
 Frog   195 VERAGLISGVRMKKIPSDENFVARGQALKKALEEDKAEGLIPIFFCATLGTTNSCAFDNLLELGP 259

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            ||...::|:|:|||||||||||||||..::|||.|||..|||.|||:|:||.:..||:..:.:..
 Frog   260 VCNAENIWMHIDAAYAGSAFICPEFRYLMKGIEFADSFNFNPHKWLLVNFDCSTFWVKKRSDLIG 324

  Fly   326 TFNVEPLYLQH--ENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388
            .|.::|:|||:  :.||:..|:.||||||.||||:||:|||.|.||:||||.|||:.|.||.:|.
 Frog   325 AFKMDPVYLQYDQQESGLVTDYRHWQIPLGRRFRSLKLWFVFRIYGVKGLQVHIRKHVGLAHEFL 389

  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453
            ..|..|.:||:.|...||||.||::|.||:.:.||:::|:...:|.:|..|...:|:||.:.:..
 Frog   390 ECVKKDDQFEICAPVILGLVCFRLKGSNELNKALLQKINNSKKIHIVPCCLGDTFVLRFAVCART 454

  Fly   454 TTLDDIVKDWMEIRQVASTVL 474
            .....|...|..|:::.:.:|
 Frog   455 VESSHIQFAWKHIKELTTELL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	214/379 (56%)
ddc	NP_001011289.1	Pyridoxal_deC	35..414	CDD:365998	214/379 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11354
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X696
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010