Protein Alignment Hdc and csad

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001007349.2
• Gene: csad / 492476
• ZFINID: ZDB-GENE-041114-36
• Length: 500
• Species: Danio rerio
• Alignment Length: 496
• Identity: 115/496 - (23%)
• Similarity: 203/496 - (40%)
• Gaps: 102/496 - (20%)

  Fly     4 KEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVMPGI 68
            :|...:|:::.:.:.::.:            |..:|.||.......||...|:...|..:....:
Zfish    37 EEILNKGRDLKEKVCEWKD------------PDQLRSLLDLELRDHGECHEKLLQRVRDVAKYSV 89

  Fly    69 THWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPDAFL 133
            ........:..|..:: ..:|.|.::.:.:|...:|:..:|....:|..|::.|..::|
Zfish    90 KTCHPRFFNQLFAGVD-YHALTGRLITETLNTSQYTYEVAPVFVLMEEEVISKLRSLVG------ 147

  Fly   134 HLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSSVEK 198
                .|:|.|:.....|.:.:..:...|..|..:...:  |...|   .|:..:.|.|:|.||:|
Zfish   148 ----WSEGDGIFCPGGSMSNMYAINVARYWAFPQVKTK--GLWAA---PRMAIFTSQQSHYSVKK 203

  Fly   199 AAL---IGLVRMRYIEADDDLAMRGKLLREAIEDDI----KQGLVPFWVCATLGTTGSCSFDNLE 256
            .|.   ||...:..::.|:.    |.::.|.:|..|    .|..|||:|.||.|||...:||.|:
Zfish   204 GAAFLGIGTENVFIVQVDES----GSMIPEDLEAKIVQAKSQDAVPFFVNATAGTTVQGAFDPLK 264

  Fly   257 EIGIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDST 321
            .|..:|..:.:|:|||||:.||.....:.|..:.|||||:|:.:||.|.|:.....:.:..||:|
Zfish   265 RIADICERNGMWMHVDAAWGGSVLFSKKHRHLVAGIERANSVTWNPHKMLLTGLQCSVILFRDTT 329

  Fly   322 --AVH-RTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRL 383
              .:| .:.....|:.|.:....::|.....|...|:...||:|.:.::.|..||.:.:
Zfish   330 NLLMHCHSAKATYLFQQDKFYDTSLDTGDKSIQCGRKVDCLKLWLMWKAIGASGLSQRV------ 388

  Fly   384 AQKFEALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHC-----------IPS 437
                      |..|.|  .|:|             .|::.||.|.:  |.|           ||.
Zfish   389 ----------DKAFAL--TRYL-------------VEEMEKRENFQ--LVCKGPFVNVCFWFIPP 426

  Fly   438 SLKGQYVIRFTITSTHTTLDDIVKDWME-IRQVASTVLEEM 477
            ||||:               :...|:.| :.:||..:.|.|
Zfish   427 SLKGK---------------ENSPDYQERLSKVAPVIKERM 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	95/387 (25%)
csad	NP_001007349.2	GadA	28..499	CDD:439846	115/496 (23%)