Protein Alignment Hdc and Sply

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 88/490 - (17%)
• Similarity: 159/490 - (32%)
• Gaps: 144/490 - (29%)

  Fly    44 ESAPIEGEPWPKIFSDVERIVMPGITHWQ----SPHMHAYFPALNSMPSLLGDMLADAINCLGFT 104
            |:.|.:|....:|...|:..:..|..:|:    |..::.|.|          |::.......|..
  Fly   101 ETLPEKGLSKEEILRLVDEHLKTGHYNWRDGRVSGAVYGYKP----------DLVELVTEVYGKA 155

  Fly   105 WASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFH 169
            ..::|...:|...|.....:::.:.....|.:|.|.|   ..||....::|..:    :|.:.|.
  Fly   156 SYTNPLHADLFPGVCKMEAEVVRMACNLFHGNSASCG---TMTTGGTESIVMAM----KAYRDFA 213

  Fly   170 ERHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQ- 233
            ..:.|.....|      ......|::.:|......:.:|.::.|.          |..|.|||:
  Fly   214 REYKGITRPNI------VVPKTVHAAFDKGGQYFNIHVRSVDVDP----------ETYEVDIKKF 262

  Fly   234 ------------GLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYA--------GS 278
                        |..|.:...|:        |::|.|..:..::.:.:||||...        .:
  Fly   263 KRAINRNTILLVGSAPNFPYGTI--------DDIEAIAALGVKYDIPVHVDACLGSFVVALVRNA 319

  Fly   279 AFICPEFRTWLRGIE--RADS------------IAFNPSKWLMVHFDATALW---VRDSTAVHRT 326
            .:....|...::|:.  .||:            |.::..|:....|..|..|   |..|..|:.:
  Fly   320 GYKLRPFDFEVKGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGS 384

  Fly   327 FNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKG----------LQRHIREGV 381
                      ...|:..                ..|..:.|:|..|          ..|:|..||
  Fly   385 ----------RAGGIIA----------------ACWATMMSFGYDGYLEATKRIVDTARYIERGV 423

  Fly   382 RLAQKFEALVLADHRFELPAKR--HLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYV 444
            |   ..:.:.:    |..||..  .||..||.|   ..:::.|.| |....|....||.
  Fly   424 R---DIDGIFI----FGKPATSVIALGSNVFDI---FRLSDSLCK-LGWNLNALQFPSG------ 471

  Fly   445 IRFTITSTHT---TLDDIVKDWMEIRQVASTVLEE 476
            |...:|..||   ..|..:.|   :|...:.::::
  Fly   472 IHLCVTDMHTQPGVADKFIAD---VRSCTAEIMKD 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	74/422 (18%)
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	80/448 (18%)