Protein Alignment Hdc and ddc

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_998507.1
• Gene: ddc / 406651
• ZFINID: ZDB-GENE-040426-2656
• Length: 480
• Species: Danio rerio
• Alignment Length: 479
• Identity: 251/479 - (52%)
• Similarity: 351/479 - (73%)
• Gaps: 3/479 - (0%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            ||..|:|:||:|||||:|||:|||.:|:|:|||.|||:|.|:||.||.|.|.:..:..|:||::|
Zfish     1 MDAAEFRRRGREMVDYVADYIENIEKRQVYPDVEPGYLRSLIPEEAPEEPESYEDVVKDIERVIM 65

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:|||.||:.:||||..:|.|::|.|:|..||.|:||:||:||||||||.::::|||||:.||:
Zfish    66 PGVTHWHSPYFYAYFPTAHSYPAMLADILCGAIGCIGFSWAASPACTELETVMLDWLGKMLKLPE 130

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            .|| ..::.:||||:|:|||||||:.|||.|::.::.....||...:.:|.::||||.|||||||
Zfish   131 DFL-AGTKGKGGGVIQSTASEATLITLLAARSKIVRLIQADHPDRSETDIISKLVAYSSDQAHSS 194

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            ||:|.|||.|||:.|..|...::||..|...:::|...||:||:.|||||||.||:||.:.|:|.
Zfish   195 VERAGLIGGVRMKKIPTDSKFSVRGDALERILKEDKAAGLIPFFFCATLGTTASCAFDCITELGP 259

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            :|....:|:|:|||||||||||||||..|.|||.|||..|||.|||:::||.:|:||:....:..
Zfish   260 ICNAEKMWMHIDAAYAGSAFICPEFRPLLNGIEFADSFNFNPHKWLLINFDCSAMWVKKRADIIG 324

  Fly   326 TFNVEPLYLQHEN--SGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388
            .|.:|||||:|::  ||:..|:.||||||.||||:||:|||.|.||:|.||.:||:.|.||::||
Zfish   325 AFKMEPLYLKHDHQESGLVTDYRHWQIPLGRRFRSLKMWFVFRMYGLKALQAYIRKHVGLAKEFE 389

  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453
            |.|.||.|||:.|...:|||.||::|.||::|.||||:|....:|.:|..|.|.:|:||.:.:..
Zfish   390 AFVRADQRFEISADVVMGLVCFRLKGPNELSENLLKRINSARKIHLVPCHLAGLFVLRFAVCARA 454

  Fly   454 TTLDDIVKDWMEIRQVASTVLEEM 477
            |....:.:.|..|||:||.:|:|:
Zfish   455 TESRHVQEAWCHIRQLASELLQEL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	204/379 (54%)
ddc	NP_998507.1	AAT_I	1..478	CDD:450240	250/477 (52%)