Protein Alignment Hdc and CG5618

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 130/583 - (22%)
• Similarity: 221/583 - (37%)
• Gaps: 177/583 - (30%)

  Fly    10 GKEMVDYIAD-------YLENI-----------------RERRVFPDVSPGYMRQLL------PE 44
            |.|.||.|.|       .|||:                 .::::.|.:.|..:::|:      .|
  Fly     7 GAETVDQIRDGLMDDWKILENVFHLLRKEDTFCVDPQKWDKQKIVPFLQPDKLKELINLKVRETE 71

  Fly    45 SAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSM-----P-SLLGDMLADAINCLGF 103
            :..:         :::|.:... :.|:.....|..|.  |.:     | .|.|.::.:|:|...:
  Fly    72 NCSL---------AEIEELCQQ-VIHYSVKTSHGRFH--NQLFGQLDPFGLAGALVTEAMNGSTY 124

  Fly   104 TWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRF 168
            |:..:|..:.:|..|:..:.|:.|          ..:|.|:.....|.:.:..::..|
  Fly   125 TYEVAPVFSLIETEVIATICKLAG----------YKEGDGIFAPGGSTSNMYGMVLAR------- 172

  Fly   169 HERHPGYQDA-EINAR-------LVAYCSDQAHSSVEKAA-LIGL-----VRMRYIEADDDLAMR 219
                  |:.| |:...       ||.:.||::|.|..||| .:||     |.:|..|       |
  Fly   173 ------YKIAPEVKTSGMFGMRPLVLFTSDESHYSFVKAANWLGLGSYNCVSVRTNE-------R 224

  Fly   220 GKLLREAIEDDIKQ----GLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAF 280
            |::|.:.:|..|.:    |..||:|..|.|||...:||::.....|...|.|||||||...|:|.
  Fly   225 GQMLLDDLEAKIAEAKARGGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWLHVDACLGGAAL 289

  Fly   281 ICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRD---------STAVHRTFNVEPLYLQH 336
            :..:.|:.:.|:|||:|.::||.|.:......:....|:         ||..|..|..:..|
  Fly   290 LSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHYLFQQDKFY--- 351

  Fly   337 ENSGVAVDFMHWQIPLSRRFRALKVWFVL--RSYGIKGLQRHIREGVRLAQKFEALVLADHRFEL 399
               .|:.|..:..:...|:..|.|.|.:|  |.||..||.  :...:.:|:..|..:
  Fly   352 ---DVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLM--VDHAIHIARLLEGKL-------- 403

  Fly   400 PAKRHLGLVVFRIRGDNEITEKLLKRL---NHRGNLHC---IPSSLKGQYVIRFTITSTHTTLDD 458
                       |.|||.       .||   .|..:..|   ||.:::        ::|...|
  Fly   404 -----------RQRGDR-------FRLVIPEHEYSNVCFWFIPKAMR--------VSSEEET--- 439

  Fly   459 IVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFAAIF 521
             .:.|..:..||..:.|:|                  |...:|::..|||..|.:...|..:|
  Fly   440 -PEWWSRLYTVAPKIKEQM------------------AHSGTLMIGYSPLKAKNLGNFFRMVF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	96/418 (23%)
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	114/483 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810