Protein Alignment Hdc and Gad1

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001261396.1
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 510
• Identity: 120/510 - (23%)
• Similarity: 210/510 - (41%)
• Gaps: 86/510 - (16%)

  Fly     5 EYRQRGKEMVDYIADYLE--NIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVMPG 67
            |.|:...:::|.:.|:::  |.|..:|.....|..|::||....|....|..::..|....:...
  Fly    32 ETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQ 96

  Fly    68 ITHWQSPHMHAYFPALNSMP--SLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            :   ::.|.|.:....|.:.  |:.|:.|....|...||:..:|....:|.:|:..:.::||
  Fly    97 V---KTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTKMREIIG--- 155

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQD---AEINARLVAYCSDQA 192
                   .|.|..:|....|.:.|...||.|       |:..|.|::   ..:...||.:.|||.
  Fly   156 -------WSGGDSILAPGGSISNLYAFLAAR-------HKMFPNYKEHGSVGLPGTLVMFTSDQC 206

  Fly   193 HSSVEK-AALIGLVRMRYIEADDDLAMRGKLLREAIEDDI----KQGLVPFWVCATLGTTGSCSF 252
            |.|::. ||:.||.....|....|  ..||::...:|..|    .:|.:||:|.||.|||...:|
  Fly   207 HYSIKSCAAVCGLGTDHCIVVPSD--EHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAF 269

  Fly   253 DNLEEIGIVCAEHHLWLHVDAAYAGSAFIC-----PEFRTWLRGIERADSIAFNPSKWL------ 306
            |::..|..:|.:::.|:|:|||:.|...:.     |.|    .|:|||||:.:||.|.:
  Fly   270 DDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRF----TGVERADSVTWNPHKLMGALLQC 330

  Fly   307 -MVHFDATALWVRDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGI 370
             .:||....|.:..:     ..:.|.|::..:...::.|.....|...|.....|:|...|:.|.
  Fly   331 STIHFKEDGLLISCN-----QMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGT 390

  Fly   371 KGLQRHIREGVRLAQ-KFEALVLADHRFELPAKRHLGLVVF-----RIRGDNEITEK-------- 421
            :|.::.....:.|.| :.:.:.....||.|..:.....|.|     |:||.....:|
  Fly   391 EGFEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDAKKEVELGKIC 455

  Fly   422 -LLK-RLNHRGNL---------------HCIPSSLKGQYVIRFTITSTHTTLDDI 459
             ::| |:..:|.|               ..|.|:...:..:.|.:...|...||:
  Fly   456 PIIKGRMMQKGTLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	100/405 (25%)
Gad1	NP_001261396.1	Pyridoxal_deC	64..434	CDD:395219	99/400 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445341
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740