Protein Alignment Hdc and gad1b

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_919400.1
• Gene: gad1b / 378441
• ZFINID: ZDB-GENE-030909-3
• Length: 587
• Species: Danio rerio
• Alignment Length: 403
• Identity: 103/403 - (25%)
• Similarity: 183/403 - (45%)
• Gaps: 62/403 - (15%)

  Fly    12 EMVDYIADYLENI--RERRVFPDVSP--------GYMRQLLPESAPIEGEPWPKIFSDVERIVMP 66
            |:|:.:.:|:...  |..:|.....|        |:..:|..:...:|     :|..|....:..
Zfish   112 EVVEILTNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDQPESLE-----QILVDCRDTLKY 171

  Fly    67 GITHWQSPHMHAYFPALNS---MPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGL 128
            |:   ::.|.. :|..|:|   :..|.|:.|....|...||:..:|....:|.:.:..:.::||.
Zfish   172 GV---RTGHPR-FFNQLSSGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQLTLKKMREIIGW 232

  Fly   129 P----DAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINA--RLVAY 187
            |    ||..     |.||.:       :.:..::..|       ::..|..:...::|  |||.:
Zfish   233 PNGDGDALF-----SPGGAI-------SNMYSVMVAR-------YKYFPEVKTKGMSAAPRLVLF 278

  Fly   188 CSDQAHSSVEKA-ALIGLVRMRYIEADDDLAMRGKLLREAIED---DIKQ-GLVPFWVCATLGTT 247
            .|:.:|.|::|| |::|..:...|....|  .||:::...:|.   |.|| |.||.:|.||.|||
Zfish   279 TSEHSHYSIKKAGAVLGFGKENVILLKTD--ERGRVIPADLEAKVIDAKQKGYVPLFVNATAGTT 341

  Fly   248 GSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDA 312
            ...:||.:.:|..:|.:::||||||.|:.|...:..:.|..|.|||||:|:.:||.|.:.|....
Zfish   342 VYGAFDPINDIADICEKYNLWLHVDGAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVPLQC 406

  Fly   313 TALWVRDSTAVHRTFNVEPLYL-----QHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKG 372
            :|:.||:...:....::...||     |::   |..|.....|...|.....|.|.:.::.|..|
Zfish   407 SAILVREKGILQGCNSMCAGYLFQPDKQYD---VTYDTGDKAIQCGRHVDIFKFWLMWKAKGTIG 468

  Fly   373 LQRHIREGVRLAQ 385
            .::||...:.|::
Zfish   469 FEQHIDRCLELSE 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	98/378 (26%)
gad1b	NP_919400.1	Pyridoxal_deC	137..511	CDD:395219	98/378 (26%)