Protein Alignment Hdc and Tdc1

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_610226.2
• Gene: Tdc1 / 35573
• FlyBaseID: FBgn0259977
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 248/511 - (48%)
• Similarity: 331/511 - (64%)
• Gaps: 12/511 - (2%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            ||.:|:|:.|||::|||..|..||.||.|.|.:.|||:::|||..||...||:..:..|.|:.:|
  Fly     1 MDVEEFRKYGKEVIDYICQYGTNIEERDVAPTLDPGYLKKLLPADAPQSPEPFKDVLEDFEQKIM 65

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:.||..|...||||:.||.||:|||||:.||..:||:|||.||..|||.|||||..|.:|||.
  Fly    66 PGVVHWNHPKFFAYFPSGNSFPSVLGDMLSSAIGSIGFSWASCPAAAELETIVMNWYAKALGLPK 130

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            ||:..:..|.|||.||.:|||..||.|:..|.|||... :......|:.....|:||.|.:||||
  Fly   131 AFVSDAPGSTGGGALQGSASECVLVSLITARARAISEL-KGQTSVHDSVFLPSLIAYASREAHSS 194

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            ||||..:.||::|.|:||:...||..|||:||::|:..||.||:|.||:||||.|:||::.|||.
  Fly   195 VEKATKMALVKLRIIDADEHGRMRVDLLRQAIQNDVNAGLTPFFVVATVGTTGGCAFDDITEIGK 259

  Fly   261 VCAE-HHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVH 324
            ||.: ..:|||||.||||::||.||.|.:..|:|.|||...||:|.|:.:|||:||||||...:.
  Fly   260 VCRQVSSIWLHVDGAYAGNSFILPEMRVFSAGLEYADSFNTNPNKLLLTNFDASALWVRDVMNLK 324

  Fly   325 RTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEA 389
            ...||.||||:||:. ..||:.|:.|||||||||||:|||.|:|||:|||.:||..:.||:|||.
  Fly   325 SALNVNPLYLRHEHL-TGVDYRHYGIPLSRRFRALKLWFVFRTYGIRGLQEYIRNHMALAKKFEM 388

  Fly   390 LVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHT 454
            ||..|.|||:....|||||.||:|..:|....||.::||.|.:|..|:...|:|||||.:|..|.
  Fly   389 LVRKDERFEVRNDVHLGLVCFRMRTGDEPNHMLLAQINHSGKMHMTPAKFNGRYVIRFCVTYEHA 453

  Fly   455 TLDDIVKDWMEIRQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSP 510
            |..||::.|.:|:..|..:|.:..:..|:.....|..|:.         |:.||:|
  Fly   454 TEKDILEAWTQIKCFAEEILRDHQLESSSVPTTPEGSERT---------SSEPLAP 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	200/378 (53%)
Tdc1	NP_610226.2	Pyridoxal_deC	35..412	CDD:278699	200/378 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	368	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	417	1.000	Inparanoid score	I444
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	1	1.000	-	-		mtm1068
orthoMCL	1	0.900	-	-		OOG6_100572
Panther	1	1.100	-	-	P	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X696
	10	9.870