Protein Alignment Hdc and Ddc

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_724163.1
• Gene: Ddc / 35190
• FlyBaseID: FBgn0000422
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 250/476 - (52%)
• Similarity: 345/476 - (72%)
• Gaps: 2/476 - (0%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            |:..|::...|.|||:||:||||||||||.|:|.|||::.|:|::||.:.|.|..:..|:||::|
  Fly    36 MEAPEFKDFAKTMVDFIAEYLENIRERRVLPEVKPGYLKPLIPDAAPEKPEKWQDVMQDIERVIM 100

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:|||.||..|||||..||.|:::.|||:.||.|:||||.:||||||||:::|:|||||:.||.
  Fly   101 PGVTHWHSPKFHAYFPTANSYPAIVADMLSGAIACIGFTWIASPACTELEVVMMDWLGKMLELPA 165

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            .||..|. .:||||:|.||||:|||.||..:.:.::...|.||.:.:..|..:||.|||||||||
  Fly   166 EFLACSG-GKGGGVIQGTASESTLVALLGAKAKKLKEVKELHPEWDEHTILGKLVGYCSDQAHSS 229

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            ||:|.|:|.|::|.:::::. .|||..|.:|||.|:.:||:||:...|||||.||:||.|:|.|.
  Fly   230 VERAGLLGGVKLRSVQSENH-RMRGAALEKAIEQDVAEGLIPFYAVVTLGTTNSCAFDYLDECGP 293

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            |..:|:||:|||||||||||||||:|..::|||.|||..|||.||::|:||.:|:|::|.:.|..
  Fly   294 VGNKHNLWIHVDAAYAGSAFICPEYRHLMKGIESADSFNFNPHKWMLVNFDCSAMWLKDPSWVVN 358

  Fly   326 TFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEAL 390
            .|||:||||:|:..|.|.|:.||||||.|||||||:|||||.||::.||.|||.....|::|..|
  Fly   359 AFNVDPLYLKHDMQGSAPDYRHWQIPLGRRFRALKLWFVLRLYGVENLQAHIRRHCNFAKQFGDL 423

  Fly   391 VLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTT 455
            .:||.||||.|:.::|||.||::|.||..|.||||:|.||::|.:|:.:|..|.:|..|.|..|.
  Fly   424 CVADSRFELAAEINMGLVCFRLKGSNERNEALLKRINGRGHIHLVPAKIKDVYFLRMAICSRFTQ 488

  Fly   456 LDDIVKDWMEIRQVASTVLEE 476
            .:|:...|.|:...|..:.:|
  Fly   489 SEDMEYSWKEVSAAADEMEQE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	206/377 (55%)
Ddc	NP_724163.1	Pyridoxal_deC	70..446	CDD:278699	206/377 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445350
Domainoid	1	1.000	368	1.000	Domainoid score	I180
eggNOG	1	0.900	-	-		E1_COG0076
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	417	1.000	Inparanoid score	I444
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223497at33208
OrthoFinder	1	1.000	-	-		FOG0000865
OrthoInspector	1	1.000	-	-		mtm1068
orthoMCL	1	0.900	-	-		OOG6_100572
Panther	1	1.100	-	-	P	PTHR11999
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X696
	11	10.800