Protein Alignment Hdc and amd

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_476592.1
• Gene: amd / 35188
• FlyBaseID: FBgn0000075
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 481
• Identity: 231/481 - (48%)
• Similarity: 323/481 - (67%)
• Gaps: 3/481 - (0%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            ||.||:|:.||..:|||||||||||:..|.|:|.|||:..|||...|.|.|.|..:..|:.|::.
  Fly     1 MDAKEFREFGKAAIDYIADYLENIRDDDVLPNVEPGYLLDLLPTEMPEEPEAWKDVLGDISRVIK 65

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:|||||||||||:|...|.||::|:|||.....:||:|..||||||||::||:||.|.:.||.
  Fly    66 PGLTHWQSPHMHAYYPTSTSYPSIVGEMLASGFGVIGFSWICSPACTELEVVVMDWLAKFLKLPA 130

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            .|.| :|...||||:|.:||||.||.:||.|.:|:..:.|.||...::|:..|||||.|||::|.
  Fly   131 HFQH-ASDGPGGGVIQGSASEAVLVAVLAAREQAVANYRESHPELSESEVRGRLVAYSSDQSNSC 194

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            :|||.::..:.:|.:.|.:|..:||..||.|||:|:..|.:|....|||||||:|::|::|.:..
  Fly   195 IEKAGVLAAMPIRLLPAGEDFVLRGDTLRGAIEEDVAAGRIPVICVATLGTTGTCAYDDIESLSA 259

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            ||.|..:||||||||||.||...|.....:|::|.||:.||..|:::|:||.:|:|:||:..|..
  Fly   260 VCEEFKVWLHVDAAYAGGAFALEECSDLRKGLDRVDSLNFNLHKFMLVNFDCSAMWLRDANKVVD 324

  Fly   326 TFNVEPLYLQHENSGVA--VDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388
            :|||:.:||:|::.|.:  .||.||||||.|||||||||...|:.|.:||:.|:|:.:.||::||
  Fly   325 SFNVDRIYLKHKHEGQSQIPDFRHWQIPLGRRFRALKVWITFRTLGAEGLRNHVRKHIELAKQFE 389

  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453
            .|||.|.||||.|.|.||||.||.:||||||.:||:||..|..::.:.:...|:..:||.:....
  Fly   390 QLVLKDSRFELVAPRALGLVCFRPKGDNEITTQLLQRLMDRKKIYMVKAEHAGRQFLRFVVCGMD 454

  Fly   454 TTLDDIVKDWMEIRQVASTVLEEMNI 479
            |...||...|.||....:.:..|.::
  Fly   455 TKASDIDFAWQEIESQLTDLQAEQSL 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	189/379 (50%)
amd	NP_476592.1	Pyridoxal_deC	35..414	CDD:395219	189/379 (50%)