Protein Alignment Hdc and CG1486

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_608450.1
• Gene: CG1486 / 33108
• FlyBaseID: FBgn0031174
• Length: 852
• Species: Drosophila melanogaster
• Alignment Length: 943
• Identity: 188/943 - (19%)
• Similarity: 303/943 - (32%)
• Gaps: 298/943 - (31%)

  Fly    21 LENIRERRVFPDVSPGYMRQLLPESA-PIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALN 84
            |||::       ||      ..|||. |:|.|.     ...||:....:           .||.:
  Fly    56 LENVK-------VS------TTPESPNPVENEE-----EAGERVTSEDL-----------LPAKH 91

  Fly    85 SMPSLLGDMLADAINCLGFTWASS------PACTELEIIVM------------------------ 119
            .:||   |:|......:.:|.:..      ||..::..:.:
  Fly    92 RVPS---DILKSLEQLVSYTDSDDDPEFPLPALDDVSHLALISHSIVAYLSHLDRQQLLRVTNSI 153

  Fly   120 -----NWLGKMIGLPDAFLHLSSQ---SQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQ 176
                 .|||.:.    .|.|.:|.   .....||:|........|                |||.
  Fly   154 SGDATRWLGTLF----HFAHPASSFHADNADAVLRTVRLAIVARC----------------PGYL 198

  Fly   177 DAEIN--ARLVAYCSD-----QAHSSVEKAALIGLVRMRYI-EADDDLAMRGKLLREAIEDDIKQ 233
            :..|.  |:...|.|:     :.|.:..:.. |.|..::.| |......|...||::.|:.|:..
  Fly   199 EGGIPALAQPTFYISENTTPMRLHYACRQLG-IPLEAIKVIPEHSQSGTMDVTLLQKQIQQDVGN 262

  Fly   234 GLVPFWVCATLGTTGSCSF-DNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADS 297
            ...|..|.|.:|.: .|.: |||..:..||..|::|||. :.:..:|.:|.:.:..:.  |...|
  Fly   263 NRTPLLVVADIGAS-LCGYVDNLLRLRDVCKAHNMWLHA-SGHGLAALVCAQNQGHVE--EVLHS 323

  Fly   298 IAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEPLYLQH---ENSGVAVDFMHWQIPLSRRFRAL 359
            :|.|...||.|    .:|               |:.|.|   :||.::. |....| ||||..||
  Fly   324 MALNLGSWLGV----PSL---------------PIVLLHRPLQNSALSA-FESDPI-LSRRLNAL 367

  Fly   360 KVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLK 424
            .:|..|::.|.|.:..      ||...|:...:.   ||:.:|         ..|        ::
  Fly   368 SLWTSLQALGRKAIAE------RLHVAFQTCSIL---FEIASK---------CEG--------IR 406

  Fly   425 RLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDDIVKDWMEIR---QVASTVLE---EMNITI-- 481
            .|:|      .|.:            .|..:|.|:::...:::   ..|:.|:.   :.:.||
  Fly   407 VLSH------TPGA------------QTGASLSDVIQSPFDVQALFDAAAPVVAYQFDGSTTIPL 453

  Fly   482 --SNRVYLKETKEKNEAFGSSLLLSNSPLSP--KVVNGSF---------------AAIFDADEFL 527
              |.........|:..|.|         |.|  |:.|.|:               ...||.:...
  Fly   454 GGSGSSAAAAAAERETAEG---------LKPLEKINNASYFDRLNSWLGQILQRDCPNFDFEVIE 509

  Fly   528 AKT------YAGVRIAHQESPSMRRRVRGILMSGKQFSLDSHMDVVVQTTLD------------- 573
            ..|      |..:.:...|.|.....:.....     ||::|:|::..|...
  Fly   510 HPTHGSCIRYCPLELGLGEQPPSSENLESFAQ-----SLEAHVDILRATIKHKARFIHLVECSDV 569

  Fly   574 ---------AGNGATR--------------TSTTNSYGHTTSAAQANSERQASIQEDNE------ 609
                     ||.|..|              .:..|........|..:::...|:.|..:
  Fly   570 LRLVPLPEWAGMGGVRFVPEGWESLLTDQAKTELNKLNIDLVEALKSTDNAFSLGEGTDGLICVR 634

  Fly   610 -----ESPEETELLSLCRTSNVPSPEHAHSLSTPSRSCSSSSHSLIHSLTQSSPRSSPVNQFRPI 669
                 ...|..|||.|..|......|::..|.|.|......    |.::|....|.|....::..
  Fly   635 FGMVTHETEVEELLDLVVTVGKSVQENSRVLDTMSEIVKKG----IEAVTADLQRESEEKLWQEG 695

  Fly   670 TLCAVPSQSQLSMPLAMPLPNRNVTVSVDSLLNPV--TTCNVYHGKRFLEPLENLA-QTSASFSS 731
            .|..||...::....:.|.....:.....:|...|  :|.|:|  |..::.....| |..|:.|.
  Fly   696 ILRHVPVVGRVFNWWSPPAKESGIKGRSLNLTQGVVESTENIY--KYHMQMTGATAHQLPANRSP 758

  Fly   732 SIFRLPTP-IATPTRESPEDPDWPAKTFSQLLLERYSSQSQSLGNNSST--ESSSLSG------G 787
                 ||| :.||.......|.:|.       :|.........|.:..|  :|...||      |
  Fly   759 -----PTPMVQTPVVAPALPPVFPT-------VEPVPGNGNGSGASEGTPVQSGEASGSMPAASG 811

  Fly   788 ATPTPTP-MSSLDELVTPLLLSFASPSQPMLSA 819
            |.|:..| .:.:|...|....|.||.:.|.|.|
  Fly   812 AAPSAAPTQNHVDHARTVSQSSAASSTVPELVA 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	91/428 (21%)
CG1486	NP_608450.1	AAT_I	159..>384	CDD:302748	68/276 (25%)
		WWbp	<725..801	CDD:304964	21/89 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445356
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840