Protein Alignment Hdc and Csad

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001346055.1
• Gene: Csad / 246277
• MGIID: 2180098
• Length: 493
• Species: Mus musculus
• Alignment Length: 476
• Identity: 125/476 - (26%)
• Similarity: 205/476 - (43%)
• Gaps: 76/476 - (15%)

  Fly    35 PGYMRQLLPESAPIEGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAIN 99
            |..::|||......:||...:|......::...:........:..|..|:. .:|.|.::.:::|
Mouse    49 PEELKQLLDLELQSQGESREQILERCRTVIHYSVKTGHPRFFNQLFSGLDP-HALAGRIITESLN 112

  Fly   100 CLGFTWASSPACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRA 164
            ...:|:..:|....:|..|:..|..::|          .:.|.||.....|.:.:..:      .
Mouse   113 TSQYTYEIAPVFVLMEEEVLKKLRALVG----------WNSGDGVFCPGGSISNMYAM------N 161

  Fly   165 IQRFHERHPGYQDAEINA--RLVAYCSDQAHSSVEK-AALIGL--VRMRYIEADDDLAMRGKLLR 224
            :.|| :|:|..:...:.|  .|..:.|.:.|.|:.| ||.:||  ..:|.::||:    ||:::.
Mouse   162 LARF-QRYPDCKQRGLRALPPLALFTSKECHYSITKGAAFLGLGTDSVRVVKADE----RGRMIP 221

  Fly   225 EAIEDDI----KQGLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAFICPEF 285
            |.:|..|    .:|.|||.|.||.|||...:||.|:.|..||..|.||.|||||:.||..:....
Mouse   222 EDLERQIILAEAEGSVPFLVSATSGTTVLGAFDPLDAIADVCQRHGLWFHVDAAWGGSVLLSRTH 286

  Fly   286 RTWLRGIERADSIAFNPSKWLMVHFDATALWVRD-STAVHRTFNVEPLYL--QHENSGVAVDFMH 347
            |..|.||:||||:|:||.|.|......:||.:|| |..:.|....:..||  |.:...||:|...
Mouse   287 RHLLDGIQRADSVAWNPHKLLAAGLQCSALLLRDTSNLLKRCHGSQASYLFQQDKFYDVALDTGD 351

  Fly   348 WQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELPAKRHLGLVVF-- 410
            ..:...||...||:|.:.::.|.:||:|.|.:...|.:.....:.....|||..:.....|.|
Mouse   352 KVVQCGRRVDCLKLWLMWKAQGGQGLERRIDQAFALTRYLVEEIKKREGFELVMEPEFVNVCFWF 416

  Fly   411 ---RIRGDNE--------------ITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDD 458
               .:||..|              :.|:::|               ||..:|.:....|......
Mouse   417 VPPSLRGKKESPDYSQRLSQVAPVLKERMVK---------------KGTMMIGYQPHGTRANFFR 466

  Fly   459 IVKDWMEIRQVASTVLEEMNI 479
            :|        ||:.:|.:.:|
Mouse   467 MV--------VANPILAQADI 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	111/394 (28%)
Csad	NP_001346055.1	DOPA_deC_like	89..481	CDD:99743	118/436 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810