Protein Alignment Hdc and Sgpl1

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001303602.1
• Gene: Sgpl1 / 20397
• MGIID: 1261415
• Length: 568
• Species: Mus musculus
• Alignment Length: 575
• Identity: 111/575 - (19%)
• Similarity: 209/575 - (36%)
• Gaps: 160/575 - (27%)

  Fly     3 FKEYRQR---GKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERI- 63
            ||..|:.   |:::...::...:::.:...|..|...|::.|     |.:|....::   :||:
Mouse    75 FKLIRKMPFIGRKIEQQVSKAKKDLVKNMPFLKVDKDYVKTL-----PAQGMGTAEV---LERLK 131

  Fly    64 ---VMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASS------PACTELEIIVM 119
               .|.|  .||..  .|.....|..|.|. ::|..|..  .|||::.      |...:||..::
Mouse   132 EYSSMDG--SWQEG--KASGAVYNGEPKLT-ELLVQAYG--EFTWSNPLHPDIFPGLRKLEAEIV 189

  Fly   120 NWLGKMI-GLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINAR 183
            .....:. |.||:.          |.:.:..:|:.|:...|.|..|:::      |.:..||.|
Mouse   190 RMTCSLFNGGPDSC----------GCVTSGGTESILMACKAYRDLALEK------GIKTPEIVA- 237

  Fly   184 LVAYCSDQAHSSVEKAA------LIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCA 242
                 .:.||::.:|||      ::.:...:.:|.|.. ||:..:.|.          ....||:
Mouse   238 -----PESAHAAFDKAAHYFGMKIVRVALKKNMEVDVQ-AMKRAISRN----------TAMLVCS 286

  Fly   243 T----LGTTGSCSFDNLEEIGIVCAEHHLWLHVDAAYAGSAFICPE-----------FRTWLRGI 292
            |    .|.     .|.:.|:..:...:.:.|||||...|...:..|           ||  ::|:
Mouse   287 TPQFPHGV-----MDPVPEVAKLAVRYKIPLHVDACLGGFLIVFMEKAGYPLEKPFDFR--VKGV 344

  Fly   293 ERADSIAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQ-------- 349
               .||:.:..|:......::.  |..|...:||:..          .|..|   ||
Mouse   345 ---TSISADTHKYGYAPKGSSV--VMYSNEKYRTYQF----------FVGAD---WQGGVYASPS 391

  Fly   350 IPLSRRFRALKV-WFVLRSYGIKGLQRHIREGVRLAQKFEA--------LVLADHRFELPAKRHL 405
            |..||....:.. |..|..:|..|.....::.::.|:..::        .:..|.:..:.|
Mouse   392 IAGSRPGGIIAACWAALMHFGENGYVEATKQIIKTARFLKSELENIKNIFIFGDPQLSVIA---- 452

  Fly   406 GLVVFRIRGDNEI-TEKLLKRLNHRG---NLHCIPSSLKGQYVIRFTITSTHTTLDDIVKDWMEI 466
                   .|.|:. ..:|...::.:|   |....|.|      |.|.||..||.
Mouse   453 -------LGSNDFDIYRLSNMMSAKGWNFNYLQFPRS------IHFCITLVHTR----------- 493

  Fly   467 RQVASTVLEEMNITISNRVYLKETKEKNEAFGSSLLLSNSPLSPKVVNGSFAAIF 521
            ::||...|:::..:::.  .:|..|.|....|:...::.:.:..|:| ...:::|
Mouse   494 KRVAIQFLKDIRESVTQ--IMKNPKAKTTGMGAIYGMAQATIDRKLV-AEISSVF 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	82/426 (19%)
Sgpl1	NP_001303602.1	DOPA_deC_like	146..507	CDD:99743	87/449 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900