Protein Alignment Hdc and spl-2

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_505372.1
• Gene: spl-2 / 181859
• WormBaseID: WBGene00006418
• Length: 542
• Species: Caenorhabditis elegans
• Alignment Length: 358
• Identity: 65/358 - (18%)
• Similarity: 124/358 - (34%)
• Gaps: 107/358 - (29%)

  Fly     2 DFKEYRQRGKEMVDYIADYL-----------ENIRERRVFPDV-SPGYMRQLLP------ESAPI 48
            :.|:..::...:||...:|.           |.:|...::.|: .|.::...:.      |....
 Worm    79 EVKDELEKSLRIVDRSTEYFTTIPSHSVGRTEVLRLAAIYDDLEGPAFLEGRVSGAVFNREDDKD 143

  Fly    49 EGEPWPKIFSDVERIVMPGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTE 113
            |.|.:.::|         |...|.:|.....||.:..|.:.:..|..:.:|      ..|..|
 Worm   144 EREMYEEVF---------GKFAWTNPLWPKLFPGVRIMEAEVVRMCCNMMN------GDSETC-- 191

  Fly   114 LEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDA 178
                                         |.:.|..|.:.|:..||.|.|.::|      |.:..
 Worm   192 -----------------------------GTMSTGGSISILLACLAHRNRLLKR------GEKYT 221

  Fly   179 EINARLVAYCSDQAHSSVEKAALIGLVRMRYIEAD------DDLAMRGKLLREAIEDDIKQGLVP 237
            |:      ......|::..|||....:::|.|..|      |.:.|:..:.:.
 Worm   222 EM------IVPSSVHAAFFKAAECFRIKVRKIPVDPVTFKVDLVKMKAAINKR------------ 268

  Fly   238 FWVCATLGTTGSCSF---DNLEEIGIVCAEHHLWLHVDAAYAGSAFICP-----EFRTWLRGIER 294
              .|..:|:..:..|   |::|.||.:..|:.:.:||||...|  |:.|     |.|...| :..
 Worm   269 --TCMLVGSAPNFPFGTVDDIEAIGQLGLEYDIPVHVDACLGG--FLLPFLEEDEIRYDFR-VPG 328

  Fly   295 ADSIAFNPSKWLMVHFDATALWVRDSTAVHRTF 327
            ..||:.:..|:.:....::.:..|:...:|..:
 Worm   329 VSSISADSHKYGLAPKGSSVVLYRNKELLHNQY 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	58/313 (19%)
spl-2	NP_505372.1	DOPA_deC_like	130..493	CDD:99743	57/307 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810