Protein Alignment Hdc and hdl-1

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_502265.2
• Gene: hdl-1 / 178129
• WormBaseID: WBGene00001839
• Length: 905
• Species: Caenorhabditis elegans
• Alignment Length: 461
• Identity: 188/461 - (40%)
• Similarity: 275/461 - (59%)
• Gaps: 13/461 - (2%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            |...::|...|::|||:....|:||..|..|.:.|||::.|||..||.:.|....|..|..::::
 Worm   343 MSRDQFRNAAKKVVDYLMKQDESIRAARCSPALKPGYLKALLPPKAPQKAEDIDDILEDYHKLIV 407

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||::|...|:.|:::||.||...||.|:|...|...||.|.|:||.||||:::|:|||:|:.||.
 Worm   408 PGLSHSSHPNFHSFYPAGNSFHCLLADLLGGHIGDAGFYWTSNPALTELEVLMMDWLGEMMALPK 472

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            .||.....|:|||.:|.:.:|:..:.|:|.||..|:|..:|....:.::|.||||||.|..|..|
 Worm   473 EFLLFPEASRGGGCMQRSDTESNFLVLVAARTDMIRRMKQRDKRLRSSDILARLVAYTSSDARRS 537

  Fly   196 V--EKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEI 258
            :  :.||.:.:|:||.:..|.:..:||..|..||..||::||:||:|.|..||:|.||||:|.|:
 Worm   538 IKMKMAAEVAMVKMRVLPTDQNFILRGDTLHAAIMADIERGLIPFFVGANFGTSGPCSFDHLHEL 602

  Fly   259 GIVCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAV 323
            |.||.||..||||||||||:|.||||.|..:|||:.|||....|||.::...|...|||||.
 Worm   603 GPVCREHGTWLHVDAAYAGTALICPEIRGLMRGIDWADSFCTTPSKLIIAVCDVCCLWVRDR--- 664

  Fly   324 HRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388
            |:        |||.:.....|.....:|.|:|..|||:||::||:|::.||..|||.:||.|...
 Worm   665 HK--------LQHASLENHPDLPFKGLPTSQRVGALKIWFMIRSFGVENLQNQIREHIRLGQVMT 721

  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453
            .::..|.|||:..|..:||:.||.:.::...:.||.|.|..||:......|:.::|||..|.|..
 Worm   722 KILQKDLRFEVCNKVVMGLICFRAKSNDMFNKALLYRCNETGNVSLASCVLQNKFVIRMCINSPK 786

  Fly   454 TTLDDI 459
            .:.:|:
 Worm   787 CSEEDL 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	164/379 (43%)
hdl-1	NP_502265.2	Pyridoxal_deC	377..746	CDD:395219	164/379 (43%)