Protein Alignment Hdc and spl-1

DIOPT Version :9

• Sequence 1: NP_001260855.1
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_499913.1
• Gene: spl-1 / 176857
• WormBaseID: WBGene00004981
• Length: 552
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 82/417 - (19%)
• Similarity: 153/417 - (36%)
• Gaps: 134/417 - (32%)

  Fly    92 DMLADAINCLG-----FTWASS------PACTELEIIVMNWLGKMIGLPDAFLHLSSQSQGGGVL 145
            |..|:.||.||     :.:::.      |...::|..::..:..:...|:         ...|.:
 Worm   146 DRHAEHINLLGKIYEKYAFSNPLHPDVFPGARKMEAELIRMVLNLYNGPE---------DSSGSV 201

  Fly   146 QTTASEATLVCLLAGRTRAIQRFHE---RHPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRM 207
            .:..:|:.::...:.|.||    |.   .||          ::..|. .||::.:|||.:..:|:
 Worm   202 TSGGTESIIMACFSYRNRA----HSLGIEHP----------VILACK-TAHAAFDKAAHLCGMRL 251

  Fly   208 RYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTT---GSCSFDNLEEIGIVCAEHHLWL 269
            |::..|.|..:..|.:...|:.:         ||..:|:.   .|.:.|.:.||..:..::.:.:
 Worm   252 RHVPVDSDNRVDLKEMERLIDSN---------VCMLVGSAPNFPSGTIDPIPEIAKLGKKYGIPV 307

  Fly   270 HVDAAYAG--------SAFICPEFRTWLRGI-------------ERADSIAFNPSKWLMVHFD-- 311
            ||||...|        :.::.|.|.....|:             .:..||....||.|. ||.
 Worm   308 HVDACLGGFMIPFMNDAGYLIPVFDFRNPGVTSISCDTHKYGCTPKGSSIVMYRSKELH-HFQYF 371

  Fly   312 ATALW---------VRDSTAVHRTFNVEPLYLQHENSGVAVDFMHWQIPLSRRFRALKVWFVLRS 367
            :.|.|         :..|.|             ..|:.||                   |..|.|
 Worm   372 SVADWCGGIYATPTIAGSRA-------------GANTAVA-------------------WATLLS 404

  Fly   368 YG----IKGLQRHIREGVRLAQKFEALVLADHRFELP-AKRHLGLVVFRIRGDN--EITEKLLK- 424
            :|    ::...:.::....||:|.|.:     ::..| .|..:.||.|...|.|  |:::|::|
 Worm   405 FGRDEYVRRCAQIVKHTRMLAEKIEKI-----KWIKPYGKSDVSLVAFSGNGVNIYEVSDKMMKL 464

  Fly   425 --RLNHRGN---LH-CIPSSLKGQYVI 445
              .||...|   :| |:..:...:.|:
 Worm   465 GWNLNTLQNPAAIHICLTINQANEEVV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_001260855.1	Pyridoxal_deC	35..413	CDD:278699	71/374 (19%)
spl-1	NP_499913.1	DOPA_deC_like	138..501	CDD:99743	82/417 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810