Protein Alignment Hdc and bas-1

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: NP_001021151.1
• Gene: bas-1 / 175778
• WormBaseID: WBGene00000239
• Length: 523
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 202/515 - (39%)
• Similarity: 294/515 - (57%)
• Gaps: 61/515 - (11%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            ||.::.|..||:|:|::|||.:.||:|:..|||.|||:..|:|..||...|.|.|||.|:|.:|:
 Worm     1 MDSQKLRTEGKKMLDFVADYWDGIRDRKPLPDVKPGYINDLVPAQAPATPEDWAKIFDDLENVVV 65

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            .|.|||..||..||||...|..|::.|:|:..|..:||||.|.|:.||||:..::|:..::|||:
 Worm    66 NGATHWHHPHFFAYFPTALSYQSIMADILSGGIAGIGFTWKSCPSMTELEMSSLDWVVDLMGLPE 130

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHER------------------------ 171
            .|.: |....|.|::|:|||::|::.::|.|...::|....
 Worm   131 HFKN-SHNGPGCGIIQSTASDSTMIAIMAARATHVERIKSEPTFMKWVSETGVGKTLKNIFDRVK 194

  Fly   172 ---------------------HPGYQDAEINARLVAYCSDQAHSSVEKAALIGLVRMRYIEADDD 215
                                 .|.:.|..:..|.|.||||||||||||.|::..||||.::
 Worm   195 VNKTLVARASVTVDDEASGMITPYFHDPTVFERFVMYCSDQAHSSVEKGAMLSAVRMRKLK---- 255

  Fly   216 LAMRGKL---------LREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGIVCAEHHLWLHV 271
             |.||.|         |:.||::|..:|.:||...||:|||.||..|.::|:|.||.|..|:|||
 Worm   256 -ATRGFLGNYGVSRETLQNAIKEDRARGYIPFMFLATVGTTCSCGVDQVDELGPVCVEEGLYLHV 319

  Fly   272 DAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHRTFNVEPLYLQH 336
            ||||||:..:|.||:..:||:|..||..||..|..||:||.:.:|.::.|.|.|.|||:.:||.|
 Worm   320 DAAYAGTFALCEEFKYLIRGMEHVDSFNFNLHKAGMVNFDCSPMWFKNGTHVSRYFNVDAVYLAH 384

  Fly   337 ENSGVAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFEALVLADHRFELPA 401
            |....|.|:.|.|:.|.||||:||:|||||:.|:..::.::|....||.:|..|:|.:.:||...
 Worm   385 EYQTTASDYRHLQVALGRRFRSLKIWFVLRNMGVDKIREYLRRTELLAAEFSKLILENGKFEHFV 449

  Fly   402 KRHLGLVVFRIRGD-NEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTHTTLDDIV 460
            .:||||..||::.. |...|||...:|....:|.:||::.|.|.:|..:.|..||||||:
 Worm   450 PQHLGLTCFRLKNSTNADNEKLCNAINDDRRIHLVPSTVHGTYFLRMVVCSQLTTLDDII 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	168/431 (39%)
bas-1	NP_001021151.1	AAT_I	35..461	CDD:450240	168/431 (39%)