Protein Alignment Hdc and LOC1280044

DIOPT Version :10

• Sequence 1: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Sequence 2: XP_061512479.1
• Gene: LOC1280044 / 1280044
• VectorBaseID: AGAMI1_013906
• Length: 522
• Species: Anopheles gambiae
• Alignment Length: 502
• Identity: 219/502 - (43%)
• Similarity: 332/502 - (66%)
• Gaps: 13/502 - (2%)

  Fly     1 MDFKEYRQRGKEMVDYIADYLENIRERRVFPDVSPGYMRQLLPESAPIEGEPWPKIFSDVERIVM 65
            ||..|:|:.|:..:|::||||||||:|.|.|.|.|||:..|||.....|.|.|..|..|.:|.::
Mosquito     4 MDINEFREFGRAAIDFVADYLENIRDRDVLPSVEPGYLHDLLPGELQNEPEDWKTIMEDFKRCIL 68

  Fly    66 PGITHWQSPHMHAYFPALNSMPSLLGDMLADAINCLGFTWASSPACTELEIIVMNWLGKMIGLPD 130
            ||:|||||||.||::|:..|..|::|:.||..:..:||:|..||.|||||:|:|||||:::.||.
Mosquito    69 PGLTHWQSPHFHAFYPSQTSYSSIVGETLAAGLGVVGFSWICSPVCTELEVIMMNWLGQLLNLPK 133

  Fly   131 AFLHLSSQSQGGGVLQTTASEATLVCLLAGRTRAIQRFHERHPGYQDAEINARLVAYCSDQAHSS 195
            :||: ..:..|||::|.:|||:.||.:||.|.:|::|...:||...:|:|..|||||.|||::|:
Mosquito   134 SFLN-CDEGNGGGIIQGSASESILVAVLAAREQAVRRLRTQHPELTEADIRGRLVAYTSDQSNSA 197

  Fly   196 VEKAALIGLVRMRYIEADDDLAMRGKLLREAIEDDIKQGLVPFWVCATLGTTGSCSFDNLEEIGI 260
            |||:.::|.::||.:.||:...:||....:|:|:|:.:||.|....|||||||:|::|||.|||.
Mosquito   198 VEKSGILGAIKMRLLPADETGILRGSTFIQAVEEDVAKGLFPVICVATLGTTGTCAYDNLAEIGP 262

  Fly   261 VCAEHHLWLHVDAAYAGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHR 325
            .|.||::|||:||||||:|...||:...::|.|.|||:.||..||:.|:||..|:|.:|:.:|.:
Mosquito   263 YCNEHNIWLHIDAAYAGAALCLPEYTHIMKGAELADSLNFNLHKWMFVNFDCCAMWFKDAGSVTQ 327

  Fly   326 TFNVEPLYLQHENSG--VAVDFMHWQIPLSRRFRALKVWFVLRSYGIKGLQRHIREGVRLAQKFE 388
            :|:|:.:||||:..|  .|.|:.||||.|.||||:||||..||:.|.:.::..||..::||.:||
Mosquito   328 SFSVDRIYLQHQFQGHSKAPDYRHWQIQLGRRFRSLKVWITLRTMGAEKIRSLIRFHIQLANRFE 392

  Fly   389 ALVLADHRFELPAKRHLGLVVFRIRGDNEITEKLLKRLNHRGNLHCIPSSLKGQYVIRFTITSTH 453
            ..|..|.|||:.... |.||.||::||:..:::||:.:..|..:..||::.:|:::|||.|....
Mosquito   393 EYVRTDDRFEVLCST-LALVCFRLKGDDARSKQLLENITKRKKIFMIPATYQGKFIIRFMICGID 456

  Fly   454 TTLDDIVKDWMEIRQVASTVL---EEMNIT------ISNRVYLKETK 491
            ..:.||...|.|:|..|..:|   |..|:.      :..::|.|.::
Mosquito   457 PQMHDIEYAWEEVRSQADLLLGVDENRNVAKQAIEPVEPKLYEKSSE 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	178/379 (47%)
LOC1280044	XP_061512479.1	None